311. (Journal Article): Presence of diabetes-inhibiting, glutamic acid decarboxylase-specific, IL-10-dependent, regulatory T cells in naive nonobese diabetic mice.

You S, Chen C, Lee WH, Brusko T, Atkinson M, Liu CP
 
ABSTRACT: Immunization of NOD mice with autoantigens such as glutamic acid decarboxylase (GAD) 221-235 peptide (p221) can induce Ag-specific CD4(+) T regulatory (Tr) cells. However, it is un...

312. (Journal Article): In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes.

Tang Q, Henriksen KJ, Bi M, Finger EB, Szot G, Ye J, Masteller EL, McDevitt H, Bonyhadi M, Bluestone JA
 
ABSTRACT: The low number of CD4+ CD25+ regulatory T cells (Tregs), their anergic phenotype, and diverse antigen specificity present major challenges to harnessing this potent tolerogenic pop...

313. (Journal Article): Tolerance Induction and Endogenous Regeneration of Pancreatic Beta-Cells in Established Autoimmune Diabetes

Sia C, Homo-Delarche F
 
ABSTRACT: Studies aimed at the understanding of the multifactorial development of autoimmune diabetes have made substantial contributions toward elucidating the molecular mechanisms that ope...

314. (Journal Article): Entero-insular axis and diabetes mellitus.

Creutzfeldt W
 
ABSTRACT: 1. The incretin effect (i.e. the difference between the insulin response after oral and i.v. glucose) is reduced in type 2 diabetes although GIP secretion is normal or exaggerated....

315. (Journal Article): Insulinotropic action of glucagonlike peptide-I-(7-37) in diabetic and nondiabetic subjects.

Nathan DM, Schreiber E, Fogel H, Mojsov S, Habener JF
 
ABSTRACT: OBJECTIVE--Whether glucagonlike peptide-I-(7-37) (GLP-I-[7-37]), a naturally occurring intestinal peptide, is insulinotropic in nondiabetic and non-insulin-dependent (type II) diab...

316. (Journal Article): Insulin independence after living-donor distal pancreatectomy and islet allotransplantation.

Matsumoto S, Okitsu T, Iwanaga Y, Noguchi H, Nagata H, Yonekawa Y, Yamada Y, Fukuda K, Tsukiyama K, Suzuki H, Kawasaki Y, Shimodaira M, Matsuoka K, Shibata T, Kasai Y, Maekawa T, Shapiro J, Tanaka K
 
ABSTRACT: Rising demand for islet transplantation will lead to severe donor shortage in the near future, especially in countries where cadaveric organ donation is scarce. We undertook a succ...

317. (Journal Article): Markedly decreased oxygen tension in transplanted rat pancreatic islets irrespective of the implantation site.

Carlsson PO, Palm F, Andersson A, Liss P
 
ABSTRACT: In this study, we syngeneically transplanted islets to three different implantation sites of diabetic and nondiabetic rats, then 9-12 weeks later we measured the blood perfusion an...

318. (Journal Article): Familial clustering of diabetic kidney disease. Evidence for genetic susceptibility to diabetic nephropathy

Seaquist ER, Goetz FC, Rich S, Barbosa J
 
ABSTRACT: Diabetic nephropathy develops in less than half of all patients with diabetes. To study heredity as a possible risk factor for diabetic kidney disease, we examined the concordance ...

319. (Journal Article): Familial factors determine the development of diabetic nephropathy in patients with IDDM

Quinn M, Angelico MC, Warram JH, Krolewski AS
 
ABSTRACT: To evaluate familial factors in the development of diabetic nephropathy in insulin-dependent diabetes mellitus (IDDM) we examined concordance for diabetic nephropathy in families w...

320. (Journal Article): Principles of type 2 diabetes mellitus therapy regarding some aspects of insulin deficiency development

[Missing indication of author names]
 
ABSTRACT: Clinical examination of 224 patients with type 2 diabetes mellitus has been carried out. The role of hyperglycemia in the development of cardiovascular complications resulting from...