161. (Journal Article): Effects of C-peptide on expression of endothelial NOS (eNOS) and inducible NOS (iNOS) in human cavernosal smooth muscle cell.

Li H, Xu L, Dunbar JC, Dhabuwala CB, Sima AAF
 
ABSTRACT: OBJECTIVES: To investigate the role of C-peptide alone or in conjunction with insulin on the expression of nitric oxide synthase (NOS) in human corpus cavernosum smooth muscle cell...

162. (Journal Article): Human C-peptide dose dependently prevents early neuropathy in the BB/Wor-rat.

Zhang W, Yorek M, Pierson CR, Murakawa Y, Breidenbach A, Sima AAF
 
ABSTRACT: In order to explore the neuroprotective and cross-species activities of C-peptide on type 1 diabetic neuropathy, spontaneously diabetic BB/W-rats were given increasing doses of hum...

163. (Journal Article): Amelioration of sensory nerve dysfunction by C-peptide in patients with type 1 diabetes.

Ekberg K, Brismar T, Johansson BL, Jonsson B, Lindström P, Wahren J

164. (Journal Article): Beneficial effects of C-peptide on incipient nephropathy and neuropathy in patients with type 1 diabetes mellitus.

Johansson B-L, Borg K, Fernquist-Forbes E, Kernell A, Odergren T, Wahren J

165. (Journal Article): Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantation.

Moberg L, Johansson H, Lukinius A, Berne C, Foss A, Kallen R, Ostraat O, Salmela K, Tibell A, Tufveson G, Elgue G, Nilsson Ekdahl K, Korsgren O, Nilsson B
 
ABSTRACT: BACKGROUND: Intraportal transplantation of pancreatic islets offers improved glycaemic control and insulin independence in type 1 diabetes mellitus, but intraportal thrombosis rema...

166. (Journal Article): Cytokines and their roles in pancreatic islet beta-cell destruction and insulin-dependent diabetes mellitus.

Rabinovitch A, Suarez-Pinzon WL
 
ABSTRACT: Insulin-dependent diabetes mellitus (IDDM) is a disease that results from autoimmune destruction of the insulin-producing beta-cells in the pancreatic islets of Langerhans. The aut...

167. (Journal Article): XIAP overexpression in islet beta-cells enhances engraftment and minimizes hypoxia-reperfusion injury.

Emamaullee JA, Liston P, Korneluk RG, Shapiro AM, Elliott J
 
ABSTRACT: Recent advances in clinical islet transplantation have allowed patients with type 1 diabetes to become insulin independent, but the procedure is limited since islets from two donor...

168. (Journal Article): Lentivirus-mediated Bcl-2 expression in betaTC-tet cells improves resistance to hypoxia and cytokine-induced apoptosis while preserving in vitro and in vivo control of insulin secretion.

Dupraz P, Rinsch C, Pralong WF, Rolland E, Zufferey R, Trono D, Thorens B
 
ABSTRACT: betaTC-tet cells are conditionally immortalized pancreatic beta cells which can confer long-term correction of hyperglycemia when transplanted in syngeneic streptozocin diabetic mi...

169. (Journal Article): Hepatocyte growth factor gene therapy for pancreatic islets in diabetes: reducing the minimal islet transplant mass required in a glucocorticoid-free rat model of allogeneic portal vein islet transplantation.

Lopez-Talavera JC, Garcia-Ocana A, Sipula I, Takane KK, Cozar-Castellano I, Stewart AF
 
ABSTRACT: Islet transplantation for diabetes is limited by the availability of human islet donors. Hepatocyte growth factor (HGF) is a potent beta-cell mitogen and survival factor and improv...

170. (Journal Article): Vulnerability of islets in the immediate posttransplantation period: dynamic changes in structure and function.

Davalli AM, Scaglia L, Zangen DH, Hollister J, Bonner-Weir S, Weir GC
 
ABSTRACT: To learn more about islet vulnerability in the immediate posttransplant period, 400 syngeneic islets were transplanted under the kidney capsule of B6AF1 mice. Three groups of recip...