411. (Journal Article): Polyclonal Anti-T-Cell Therapy for Type 1 Diabetes Mellitus of Recent Onset

Saudek F, Havrdova T, Boucek P, Karasova L, Novota P, Skibova J
 
ABSTRACT: The destruction of pancreatic beta-cells in type 1 diabetes mellitus is mediated by autoreactive T-lymphocyte clones. We initiated a prospective randomized controlled trial of poly...

412. (Journal Article): Dynamics of pathogenic and suppressor T cells in autoimmune diabetes development.

Gregori S, Giarratana N, Smiroldo S, Adorini L
 
ABSTRACT: In the nonobese diabetic (NOD) mouse, pathogenic and suppressor CD4(+) T cells can be distinguished by the constitutive expression of CD25. In this study, we demonstrate that the p...

413. (Journal Article): Global and societal implications of the diabetes epidemic

Zimmet P, Alberti KG, Shaw J
 
ABSTRACT: Changes in human behaviour and lifestyle over the last century have resulted in a dramatic increase in the incidence of diabetes worldwide. The epidemic is chiefly of type 2 diabet...

414. (Journal Article): Modulation of Adipoinsular Axis in Prediabetic ZDF rats by Diazoxide

Alemzadeh R, Tushaus KM
 
ABSTRACT: Dysregulation of the adipoinsular axis in male obese Zucker diabetic fatty (ZDF, fa/fa) rats, a model of type 2 diabetes, results in chronic hyperinsulinemia and increased de novo ...

415. (Journal Article): Albumin excretion in diabetic patients in the setting of acute myocardial infarction: association with 3-year mortality

Berton G, Cordiano R, Palmieri R, De Toni R, Guarnieri GL, Palatini P
 
ABSTRACT: AIMS/HYPOTHESIS. Diabetes mellitus is associated with increased mortality in subjects with acute myocardial infarction (AMI). We aimed to estimate the risk of mortality in AMI pati...

416. (Journal Article): Glucagon-like peptide 1 and its derivatives in the treatment of diabetes.

Nauck MA, Meier JJ
 
ABSTRACT: Glucagon-like peptide 1 (GLP-1) was discovered as an insulinotropic gut hormone, suggesting a physiological role as an incretin hormone, i.e., being responsible, in part, for the h...

417. (Journal Article): Effect on glycemic control of exenatide (synthetic exendin-4) additive to existing metformin and/or sulfonylurea treatment in patients with type 2 diabetes.

Fineman MS, Bicsak TA, Shen LZ, Taylor K, Gaines E, Varns A, Kim D, Baron AD
 
ABSTRACT: OBJECTIVE: AC2993 (synthetic exendin-4; exenatide) is a peptide that enhances glucose-dependent insulin secretion, suppresses inappropriately elevated glucagon secretion, and slows...

418. (Journal Article): The effect of liraglutide, a long-acting glucagon-like peptide 1 derivative, on glycemic control, body composition, and 24-h energy expenditure in patients with type 2 diabetes.

Harder H, Nielsen L, Tu DT, Astrup A
 
ABSTRACT: OBJECTIVE: Glucagon-like peptide (GLP)-1 is a gut hormone that exerts incretin effects and suppresses food intake in humans, but its therapeutic use is limited due to its short hal...

419. (Journal Article): Glycemic control with diet, sulfonylurea, metformin, or insulin in patients with type 2 diabetes mellitus: progressive requirement for multiple therapies (UKPDS 49).

Turner RC, Cull CA, Frighi V, Holman RR
 
ABSTRACT: CONTEXT: Treatment with diet alone, insulin, sulfonylurea, or metformin is known to improve glycemia in patients with type 2 diabetes mellitus, but which treatment most frequently ...

420. (Journal Article): The Influence of Physicians' Practice Management Strategies and Financial Arrangements on Quality of Care Among Patients With Diabetes

Keating NL, Landrum MB, Landon BE, Ayanian JZ, Borbas C, Wolf R, Guadagnoli E
 
ABSTRACT: CONTEXT:: Health care organizations use many strategies to influence physician behavior and the care delivered, but the effect of such strategies on quality is not known. OBJECTIVE...