271. (Journal Article): Type 2 Diabetes – Failure, Blame and Guilt in the Adoption of Insulin Therapy

Phillips P
 
ABSTRACT: Type 2 Diabetes is a progressive disease with an insidious onset, including decreased first-phase insulin secretion and mild forms of hyperinsulinemia caused by heterogenous factor...

272. (Journal Article): Elimination of Dietary Gluten and Development of Type 1 Diabetes in High Risk Subjects

Fuchtenbusch M, Ziegler AG, Hummel M
 
ABSTRACT: Removal of dietary gluten is associated with a lower frequency of type 1 diabetes (T1D) in patients with celiac disease. Therefore, we performed a pilot study in which seven islet-...

273. (Journal Article): Insulinotropic and Anti-Inflammatory Effects of Rosiglitazone in Experimental Autoimmune Diabetes

Awara WM, El-Sisi AE, Mohamed El-Refaei M, El-Naa MM, El-Desoky K
 
ABSTRACT: Cytokines and nitric oxide (NO) are involved in the pathogenesis of autoimmune diabetes mellitus (DM). Rosiglitazone is an insulin-sensitizing drug that is a ligand for the nuclear...

274. (Journal Article): Apoptosis in Autoimmune Diabetes: The Fate of β-Cells in the Cleft between Life and Death

Sia C, Hanninen A
 
ABSTRACT: Cytokine-induced β-cell death is the end-stage event in the pathogenesis of autoimmune diabetes. Beside cytokines, several pro-apoptotic pathways mediated through nitric oxide, re...

275. (Journal Article): Adult human cytokeratin 19-positive cells reexpress insulin promoter factor 1 in vitro.

Gmyr V, Kerr-Conte J, Belaich S, Vandewalle B, Leteurtre E, Vantyghem MC, Lecomte-Houcke M, Proye C, Lefebvre J, Pattou F
 
ABSTRACT: Human pancreatic cells with a typical ductal phenotype and potential to proliferate can be obtained in vitro, but the differentiation capacity of these putative human pancreatic st...

276. (Journal Article): Immunotherapy After Recent-Onset Type 1 Diabetes: Combinatorial Treatment for Achieving Long-Term Remission in Humans?

Bresson D, von Herrath M
 
ABSTRACT: Insulin-dependent diabetes mellitus (IDDM), or type 1 diabetes mellitus (TlDM), is one of the most common autoimmune diseases. This chronic disorder is thought to be caused by auto...

277. (Journal Article): Prospects for gene therapy of insulin-dependent diabetes mellitus.

Efrat S
 
ABSTRACT: The application of gene therapy to type I (insulin-dependent) diabetes mellitus awaits improvements in gene transfer technologies and the development of better tools for accurate d...

278. (Journal Article): Human islet glucokinase gene: isolation and sequence analysis of full-length cDNA.

Koranyi LI, Tanizawa Y, Welling CM, Rabin DU, Permutt MA
 
ABSTRACT: Pancreatic islet glucokinase (ATP:D-hexose-6-phosphotransferase) cDNAs were isolated from a human islet cDNA library in lambda-gt11. One clone (hlGLK2), 2723 bp plus additional pol...

279. (Journal Article): The effect of intensive treatment of diabetes on development and progression of long-term complications in insulin-dependent diabetes mellitus.

The Diabetes Control and Complications Trial Research Group

280. (Journal Article): Mechanism of disease: glucose transporters and insulin action: implication for insulin resistance and diabetes mellitus.

Shepherd PR, Kahn BB
 
ABSTRACT: Insulin was discovered more than 75 years ago, but only recently have we begun to understand the mechanisms by which insulin promotes the uptake of glucose into cells. This review ...