441. (Journal Article): Concordance for type 2 (non-insulin-dependent) diabetes mellitus in male twins

Newman B, Selby JV, King MC, Slemenda C, Fabsitz R, Friedman GD
 
ABSTRACT: Concordance for Type 2 (non-insulin-dependent) diabetes was determined in 250 monozygotic and 264 dizygotic white male twin pairs who participated in the National Heart, Lung, and ...

442. (Journal Article): Defective mutations in the insulin promoter factor-1 (IPF-1) gene in late-onset type 2 diabetes mellitus

Hani EH, Stoffers DA, Chevre JC, Durand E, Stanojevic V, Dina C, Habener JF, Froguel P
 
ABSTRACT: Type 2 diabetes mellitus is a common disabling disease with onset in middle-aged individuals, caused by an imbalance between insulin production and action. Genetic studies point to...

443. (Journal Article): Association of adiponectin mutation with type 2 diabetes: a candidate gene for the insulin resistance syndrome

Kondo H, Shimomura I, Matsukawa Y, Kumada M, Takahashi M, Matsuda M, Ouchi N, Kihara S, Kawamoto T, Sumitsuji S, Funahashi T, Matsuzawa Y
 
ABSTRACT: Adiponectin, also referred to as AdipoQ or ACRP30, is a plasma protein produced and secreted exclusively from adipose tissue. The protein contains a collagen-like domain and a C1q-...

444. (Journal Article): Association of resistin gene 3'-untranslated region +62G-->A polymorphism with type 2 diabetes and hypertension in a Chinese population.

Tan MS, Chang SY, Chang DM, Tsai JC, Lee YJ
 
ABSTRACT: Resistin, a recently discovered polypeptide, antagonizes insulin action and may play a part in the pathogenesis of insulin resistance. This study investigates whether resistin gene...

445. (Journal Article): Clinical outcomes and insulin secretion after islet transplantation with the Edmonton Protocol.

Ryan EA, Lakey JR, Rajotte RV, Korbutt GS, Kin T, Imes S, Rabinovitch A, Elliot JF, Bigam D, et al
 
ABSTRACT: Islet transplantation offers the prospect of good glycemic control without major surgical risks. After our initial report of successful islet transplantation, we now provide furthe...

446. (Journal Article): Physician Process and Patient Outcome Measures for Diabetes Care: Relationships to Organizational Characteristics

Ward MM, Yankey JW, Vaughn TE, BootsMiller BJ, Flach SD, Welke KF, Pendergast JF, Perlin J, Doebbeling BN
 
ABSTRACT: BACKGROUND:: Optimal diabetes management relies on providers adhering to evidence-based practice guidelines in the processes of care delivery and patients adhering to self-manageme...

447. (Journal Article): Interleukin-11 inhibits NF-kappaB and AP-1 activation in islets and prevents diabetes induced with streptozotocin in mice.

Lgssiar A, Hassan M, Schott-Ohly P, Friesen N, Nicoletti F, Trepicchio WL, Gleichmann H
 
ABSTRACT: This laboratory has reported that multiple low doses of streptozotocin (MLD-STZ) similarly upregulate the T helper (Th)1-type proinflammatory cytokines tumor necrosis factor (TNF)-...

448. (Journal Article): Rationale, design and recruitment characteristics of a large, simple international trial of diabetes prevention: the DREAM trial

No indication of authors
 
ABSTRACT: AIMS/HYPOTHESIS. Diabetes is a rapidly rising independent risk factor for atherosclerosis and serious illness. This risk can be reduced by lifestyle changes and/or various drugs. N...

449. (Journal Article): A new subtype of autosomal dominant diabetes attributable to a mutation in the gene for sulfonylurea receptor 1

Huopio H, Otonkoski T, Vauhkonen I, Reimann F, Ashcroft FM, Laakso M
 
ABSTRACT: BACKGROUND: ATP-sensitive potassium (KATP) channels are major regulators of glucose-induced insulin secretion in pancreatic beta cells. We have described a dominant heterozygous mu...

450. (Journal Article): Hypercalciuria, hyperphosphaturia, and growth retardation in children with diabetes mellitus.

Malone JI, Lowitt S, Duncan JA, Shah SC, Vargas A, Root AW
 
ABSTRACT: The role of hypercalciuria and hyperphosphaturia in the growth retardation of children with diabetes mellitus was investigated in 157 children with diabetes whose mean height was l...