321. (Journal Article): Immunohistochemical characterization of monocytes-macrophages and dendritic cells involved in the initiation of the insulitis and beta-cell destruction in NOD mice.

Jansen A, Homo-Delarche F, Hooijkaas H, Leenen PJ, Dardenne M, Drexhage HA
 
ABSTRACT: This immunohistochemical study describes the infiltration pattern of monocytes-macrophages and dendritic cells during the development of insulitis and diabetes in the NOD mouse. A ...

322. (Journal Article): Genetic variation in the hepatocyte nuclear factor-1 alpha gene in Danish Caucasians with late-onset NIDDM

Urhammer SA, Rasmussen SK, Kaisaki PJ, Oda N, Yamagata K, Moller AM, Fridberg M, Hansen L, Hansen T, Bell GI, Pedersen O
 
ABSTRACT: Non-insulin-dependent diabetes mellitus (NIDDM) is a phenotypically and genetically heterogeneous disorder. A recent random genome mapping study has localized a locus termed NIDDM2...

323. (Journal Article): beta-Cell death and mass in syngeneically transplanted islets exposed to short- and long-term hyperglycemia.

Biarnes M, Montolio M, Nacher V, Raurell M, Soler J, Montanya E
 
ABSTRACT: We studied the effects of hyperglycemia on beta-cell death and mass in syngeneically transplanted islets. Six groups of STZ-induced diabetic C57BL/6 mice were transplanted with 100...

324. (Journal Article): Familial clustering of diabetic nephropathy in Brazilian type 2 diabetic patients

Canani LH, Gerchman F, Gross JL
 
ABSTRACT: There is evidence for genetic predisposition to diabetic nephropathy in type 1 diabetic patients. However, there are few studies on type 2 diabetic patients, and most of those have...

325. (Journal Article): Renal structure and function in insulin-dependent diabetes mellitus and type I membranoproliferative glomerulonephritis in humans.

Mauer SM, Lane P, Hattori M, Fioretto P, Steffes MW
 
ABSTRACT: Renal pathological changes of diabetes include thickening of all renal extracellular basement membranes and the mesangial matrix and, to a lesser extent, mesangial cell expansion. ...

326. (Journal Article): Osteoporosis and diabetes.

Chau DL, Edelman SV, Chandran M
 
ABSTRACT: Osteoporosis is the most prevalent metabolic bone disease in the United States. Although the disease has historically been reported mostly in white women, it can affect individuals...

327. (Journal Article): Prevalence and magnitude of osteopenia associated with insulin-dependent diabetes mellitus.

Kayath MJ, Dib SA, Vieiaa JG
 
ABSTRACT: The authors evaluated the prevalence, magnitude, and contributing factors for osteopenia in insulin-dependent diabetes mellitus (IDDM). We measured bone mineral density (BMD) in th...

328. (Journal Article): ALDH2/ADH2 Polymorphism Associated with Vasculopathy and Neuropathy in Type 2 Diabetes

Suzuki Y, Taniyama M, Muramatsu T, Higuchi S, Ohta S, Atsumi Y, Matsuoka K
 
ABSTRACT: In the history of diabetes, chlorpropamide alcohol flushing test (CPAF) was a big topic in the 1970s to 1980s. Alcohol tolerance after chlorpropamide has prognostic significance, w...

329. (Journal Article): New Therapeutic Strategies for the Treatment of Type 2 Diabetes Mellitus Based on Incretins

Gallwitz B
 
ABSTRACT: Orally ingested glucose leads to a greater insulin response compared to intravenously administered glucose leading to identical postprandial plasma glucose excursions, a phenomenon...

330. (Journal Article): Islet Amyloid, Metabolic Syndrome, and the Natural Progressive History of Type 2 Diabetes Mellitus

Hayden MR
 
ABSTRACT: The presence of amyloid within the islet of the pancreas may be one of the best kept secrets in clinical medicine and translation of this century old finding may help to better und...