181. (Journal Article): Epidemiology and genetics of diabetes mellitus.

Warram JH, Rich SS, Krolewski A

182. (Journal Article): Local expression of B7-H1 promotes organ-specific autoimmunity and transplant rejection.

Subudhi SK, Zhou P, Yerian LM, Chin RK, Lo JC, Anders RA, Sun Y, Chen L, Wang Y, Alegre ML, Fu YX
 
ABSTRACT: A number of studies have suggested B7-H1, a B7 family member, inhibits T cell responses. Therefore, its expression on nonlymphoid tissues has been proposed to prevent T cell-mediat...

183. (Journal Article): A second pathway for regeneration of adult exocrine and endocrine pancreas.

Bonner-Weir S, Baxter LA, Schuppin GT, Smith FE
 
ABSTRACT: Substantial regeneration of both the endocrine and exocrine pancreas occurs after a 90% partial pancreatectomy in the young adult rat. We have reported previously that replication ...

184. (Journal Article): Regeneration of pancreatic beta cells from intra-islet precursor cells in an experimental model of diabetes.

Guz Y, Nasir I, Teitelman G
 
ABSTRACT: We previously reported that new beta cells differentiated in pancreatic islets of mice in which diabetes was produced by injection of a high dose of the beta cell toxin streptozoto...

185. (Journal Article): In vitro cultivation of human islets from expanded ductal tissue.

Bonner-Weir S, Taneja M, Weir GC, Tatarkiewics K, Song KH, Sharma A, O'Neil JJ
 
ABSTRACT: A major obstacle to successful islet transplantation for both type 1 and 2 diabetes is an inadequate supply of insulin-producing tissue. This need for transplantable human islets h...

186. (Journal Article): Nestin-positive progenitor cells derived from adult human pancreatic islets of Langerhans contain side population (SP) cells defined by expression of the ABCG2 (BCRP1) ATP-binding cassette transporter.

Lechner A, Leech CA, Abraham EJ, Nolan AL, Habener JF
 
ABSTRACT: The disease diabetes mellitus arises as a consequence of a failure of the beta-cells in the islets of Langerhans of the pancreas to produce insulin in the amounts required to meet ...

187. (Journal Article): Acid beta-galactosidase: a developmentally regulated marker of endocrine cell precursors in the human fetal pancreas.

Beattie GM, Levine F, Mally MI, Otonkoski T, O'Brien JS, Salomon DR, Hayek A
 
ABSTRACT: Isolation of endocrine cell precursors from the human fetal pancreas will be important to the study of islet cytodifferentiation and eventually for islet transplantation in insulin...

188. (Journal Article): Insulin-Producing Cells from Tissue Stem/Progenitor Cells: Are Autologous Cells Preferable to Allogeneic?

Efrat S
 
ABSTRACT: Type 1 diabetes is caused by autoimmune destruction of the pancreatic islet insulin-producing β-cells. Insulin administration does not prevent long-term complications of the disea...

189. (Journal Article): Accelerated telomere shortening and senescence in human pancreatic islet cells stimulated to divide in vitro.

Halvorsen TL, Beattie GM, Lopez AD, Hayek A, Levine F
 
ABSTRACT: Widespread application of beta-cell replacement strategies for diabetes is dependent upon the availability of an unlimited supply of cells exhibiting appropriate glucose-responsive...

190. (Journal Article): The efficacy of Silybum marianum (L.) Gaertn. (silymarin) in the treatment of type II diabetes: a randomized, double-blind, placebo-controlled, clinical trial.

Huseini HF, Larijani B, Heshmat R, Fakhrzadeh H, Radjabipour B, Toliat T, Raza M.
 
ABSTRACT: Oxidative stresses are increasingly implicated in the pathogenesis of diabetic complications which may either cause direct pancreatic beta-cell damage or lead to metabolic abnormal...