361. (Journal Article): Diabetes 2001 Vital Statistics.

American Diabetes Association

362. (Journal Article): The effect of intensive diabetes treatment on the development and progression of long-term complications in insulin dependent diabetes mellitus: The diabetes control and com-plications trial.

The Diabetes Control and Complications Trial Research Group

363. (Journal Article): Islet Amyloid, Metabolic Syndrome, and the Natural Progressive History of Type 2 Diabetes Mellitus

Hayden MR
 
ABSTRACT: The presence of amyloid within the islet of the pancreas may be one of the best kept secrets in clinical medicine and translation of this century old finding may help to better und...

364. (Journal Article): New Therapeutic Strategies for the Treatment of Type 2 Diabetes Mellitus Based on Incretins

Gallwitz B
 
ABSTRACT: Orally ingested glucose leads to a greater insulin response compared to intravenously administered glucose leading to identical postprandial plasma glucose excursions, a phenomenon...

365. (Journal Article): beta-Cell death and mass in syngeneically transplanted islets exposed to short- and long-term hyperglycemia.

Biarnes M, Montolio M, Nacher V, Raurell M, Soler J, Montanya E
 
ABSTRACT: We studied the effects of hyperglycemia on beta-cell death and mass in syngeneically transplanted islets. Six groups of STZ-induced diabetic C57BL/6 mice were transplanted with 100...

366. (Journal Article): Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes.

Wang J, Yoshida T, Nakaki F, Hiai H, Okazaki T, Honjo T
 
ABSTRACT: Mice deficient in programmed cell death 1 (PD-1, Pdcd1), an immunoinhibitory receptor belonging to the CD28/cytotoxic T lymphocyte-associated antigen-4 family, spontaneously develo...

367. (Journal Article): Benefits and risks of solitary islet transplantation for type 1 diabetes using steroid-sparing immunosuppression: the National Institutes of Health experience.

Hirshberg B, Rother KI, Digon BJ 3rd, Lee J, Gaglia JL, Hines K, Read EJ, Chang R, Wood BJ, Harlan DM
 
ABSTRACT: OBJECTIVE: The aim of this study was to describe the National Institutes of Health's experience initiating an islet isolation and transplantation center, including descriptions of ...

368. (Journal Article): Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes.

Zulewski H, Abraham EJ, Gerlach MJ, Daniel PB, Moritz W, Muller B, Vallejo M, Thomas MK, Habener JF
 
ABSTRACT: The endocrine cells of the rat pancreatic islets of Langerhans, including insulin-producing beta-cells, turn over every 40-50 days by processes of apoptosis and the proliferation a...

369. (Journal Article): Insulin production by human embryonic stem cells.

Assady S, Maor G, Amit M, Itskovitz-Eldor J, Skorecki KL, Tzukerman M
 
ABSTRACT: Type 1 diabetes generally results from autoimmune destruction of pancreatic islet beta-cells, with consequent absolute insulin deficiency and complete dependence on exogenous insul...

370. (Journal Article): The Role of Regulatory T Cell Defects in Type I Diabetes and the Potential of these Cells for Therapy

Thomas D, Zaccone P, Cooke A
 
ABSTRACT: Type I diabetes is increasing in incidence in developed countries [1]. Diabetes arises from a breakdown of tolerance to islet antigens, resulting in T cell-driven destruction of th...