201. (Journal Article): X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy.

Wildin RS, Ramsdell F, Peake J, Faravelli F, Casanova JL, Buist N, Levy-Lahad E, Mazzella M, Goulet O, Perroni L et al
 
ABSTRACT: To determine whether human X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome (IPEX; MIM 304930) is the genetic equivalent of the scurfy (sf) mouse, we se...

202. (Journal Article): Differences in the pharmacokinetics of peroxisome proliferator-activated receptor agonists in genetically obese zucker and sprague-dawley rats: implications of decreased glucuronidation in obese zucker rats

Kim MS, Wang S, Shen Z, Kochansky CJ, Strauss JR, Franklin RB, Vincent SH
 
ABSTRACT: Genetically obese Zucker rats exhibit symptoms similar to those of obese patients with insulin-resistance or Type II diabetes; therefore, they have been used as a genetic model to ...

203. (Journal Article): Intracellular magnesium and insulin resistance

Takaya J, Higashino H, Kobayashi Y
 
ABSTRACT: Magnesium, the second most abundant intracellular divalent cation, is a cofactor of many enzymes involved in glucose metabolism. Magnesium has an important role in insulin action, ...

204. (Journal Article): Maternally transmitted diabetes and deafness associated with a 10.4 kb mitochondrial DNA deletion

Ballinger SW, Shoffner JM, Hedaya EV, Trounce I, Polak MA, Koontz DA, Wallace DC
 
ABSTRACT: Diabetes mellitus (DM) is one of the most common chronic disorders of children and adults. Several reports have suggested an increased incidence of maternal transmission in some fo...

205. (Journal Article): Long-term Immunosuppression, Without Maintenance Prednisone, After Kidney Transplantation

Matas AJ, Kandaswamy R, Humar A, Payne WD, Dunn DL, Najarian JS, Gruessner RW, Gillingham KJ, McHugh LE, Sutherland DE
 
ABSTRACT: BACKGROUND:: Concern exists that prednisone-free maintenance immunosuppression in kidney transplant recipients will increase acute and/or chronic rejection. METHODS:: From October ...

206. (Journal Article): Expression of calbindin-D(28k) in a pancreatic islet beta-cell line protects against cytokine-induced apoptosis and necrosis.

Rabinovitch A, Suarez-Pinzon WL, Sooy K, Strynadka K, Christakos S
 
ABSTRACT: Cytokines produced by immune system cells that infiltrate pancreatic islets are candidate mediators of islet beta-cell destruction in autoimmune (type 1) diabetes mellitus. Because...

207. (Journal Article): Glucagon-like peptide-1, a gastrointestinal hormone with a pharmaceutical potential.

Holst JJ
 
ABSTRACT: Glucagon-like peptide-1 (GLP-1) is an insulinotropic hormone secreted from endocrine cells in the gut mucosa in response to meal ingestion. It is an important incretin hormone; mic...

208. (Journal Article): The potential role of glucagon-like peptide 1 in diabetes.

Meier JJ, Nauck MA
 
ABSTRACT: The incretin hormone glucagon-like peptide 1 (GLP-1) has a promising potential for the treatment of type 2 diabetes due to its glucose-dependent insulinotropic and glucagonostatic ...

209. (Journal Article): In vivo gene transfer to pancreatic Beta cells by systemic delivery of adenoviral vectors

Ayuso E, Chillon M, Agudo J, Haurigot V, Bosch A, Carretero A, Otaegui PJ, Bosch F
 
ABSTRACT: Type 1 diabetes results from autoimmune destruction of pancreatic beta cells. This process might be reversed by genetically engineering the endocrine pancreas in vivo to express fa...

210. (Journal Article): Factors influencing Islet of Langerhans graft function and monitoring.

Pileggi A, Ricordi C, Alessiani M, Inverardi L
 
ABSTRACT: Transplantation of islet of Langerhans represents a viable therapeutic option for insulin-dependent diabetes mellitus. Dramatic progress has been recently reported with the introdu...