441. (Journal Article): Defective mutations in the insulin promoter factor-1 (IPF-1) gene in late-onset type 2 diabetes mellitus

Hani EH, Stoffers DA, Chevre JC, Durand E, Stanojevic V, Dina C, Habener JF, Froguel P
 
ABSTRACT: Type 2 diabetes mellitus is a common disabling disease with onset in middle-aged individuals, caused by an imbalance between insulin production and action. Genetic studies point to...

442. (Journal Article): Concordance for type 2 (non-insulin-dependent) diabetes mellitus in male twins

Newman B, Selby JV, King MC, Slemenda C, Fabsitz R, Friedman GD
 
ABSTRACT: Concordance for Type 2 (non-insulin-dependent) diabetes was determined in 250 monozygotic and 264 dizygotic white male twin pairs who participated in the National Heart, Lung, and ...

443. (Journal Article): Glycaemic control in a type 1 diabetes clinic for younger adults

Saunders SA, Wallymahmed M, MacFarlane IA
 
ABSTRACT: BACKGROUND: In the Diabetes Control and Complications Trial (DCCT, 1993) tight diabetes control (HbA1c <7%) was associated with significantly less microvascular complications co...

444. (Journal Article): A Single Treatment with IL-4 via Retrovirally Transduced Lymphocytes Partially Protects Against Diabetes in BioBreeding (BB) Rats

Zipris D, Karnieli E
 
ABSTRACT: CONTEXT: Type 1 diabetes mellitus is a T cell mediated autoimmune disease with no known methods of prevention. The BioBreeding rat is used as an animal model for the study of human...

445. (Journal Article): Mutations in MODY Genes Are not Common Cause of Early-Onset Type 2 Diabetes in Mexican Families

Domínguez-López A, Miliar-García A, Segura-Kato YX, Riba L, Esparza-López J, Ramírez-Jiménez S, Rodríguez-Torres M, Canizales-Quinteros S, Cabrera-Vásquez S, Fragoso-Ontiveros V, Aguilar-Salinas CA, Altamirano-Ustamante N, Calzada-León R, Robles-Valdés C, Bravo-Ríos LE, Tusié-Luna MT
 
ABSTRACT: CONTEXT: Maturity-onset diabetes of the young (MODY) is a monogenic form of diabetes mellitus characterized by autosomal dominant inheritance, early age of onset and a primary insu...

446. (Journal Article): Rationale, design and recruitment characteristics of a large, simple international trial of diabetes prevention: the DREAM trial

No indication of authors
 
ABSTRACT: AIMS/HYPOTHESIS. Diabetes is a rapidly rising independent risk factor for atherosclerosis and serious illness. This risk can be reduced by lifestyle changes and/or various drugs. N...

447. (Journal Article): Interleukin-11 inhibits NF-kappaB and AP-1 activation in islets and prevents diabetes induced with streptozotocin in mice.

Lgssiar A, Hassan M, Schott-Ohly P, Friesen N, Nicoletti F, Trepicchio WL, Gleichmann H
 
ABSTRACT: This laboratory has reported that multiple low doses of streptozotocin (MLD-STZ) similarly upregulate the T helper (Th)1-type proinflammatory cytokines tumor necrosis factor (TNF)-...

448. (Journal Article): Physician Process and Patient Outcome Measures for Diabetes Care: Relationships to Organizational Characteristics

Ward MM, Yankey JW, Vaughn TE, BootsMiller BJ, Flach SD, Welke KF, Pendergast JF, Perlin J, Doebbeling BN
 
ABSTRACT: BACKGROUND:: Optimal diabetes management relies on providers adhering to evidence-based practice guidelines in the processes of care delivery and patients adhering to self-manageme...

449. (Journal Article): A new subtype of autosomal dominant diabetes attributable to a mutation in the gene for sulfonylurea receptor 1

Huopio H, Otonkoski T, Vauhkonen I, Reimann F, Ashcroft FM, Laakso M
 
ABSTRACT: BACKGROUND: ATP-sensitive potassium (KATP) channels are major regulators of glucose-induced insulin secretion in pancreatic beta cells. We have described a dominant heterozygous mu...

450. (Journal Article): Hypercalciuria, hyperphosphaturia, and growth retardation in children with diabetes mellitus.

Malone JI, Lowitt S, Duncan JA, Shah SC, Vargas A, Root AW
 
ABSTRACT: The role of hypercalciuria and hyperphosphaturia in the growth retardation of children with diabetes mellitus was investigated in 157 children with diabetes whose mean height was l...