361. (Journal Article): B Cells in Autoimmune Diabetes

Wong FS, Wen L
 
ABSTRACT: Autoantibodies have been used as good markers for the prediction of future development of type 1 diabetes mellitus (T1DM), but are not thought to be pathogenic in this disease. The...

362. (Journal Article): Gastric inhibitory polypeptide: the neglected incretin revisited.

Meier JJ, Nauck MA, Schmidt WE, Gallwitz B
 
ABSTRACT: After the ingestion of fat- and glucose-rich meals, gut hormones are secreted into the circulation in order to stimulate insulin secretion. This so-called "incretin effect&quo...

363. (Journal Article): Renal structure and function in insulin-dependent diabetes mellitus and type I membranoproliferative glomerulonephritis in humans.

Mauer SM, Lane P, Hattori M, Fioretto P, Steffes MW
 
ABSTRACT: Renal pathological changes of diabetes include thickening of all renal extracellular basement membranes and the mesangial matrix and, to a lesser extent, mesangial cell expansion. ...

364. (Journal Article): Osteoporosis and diabetes.

Chau DL, Edelman SV, Chandran M
 
ABSTRACT: Osteoporosis is the most prevalent metabolic bone disease in the United States. Although the disease has historically been reported mostly in white women, it can affect individuals...

365. (Journal Article): Genes Mediating Environment Interactions in Type 1 Diabetes

Biros E, Jordan MA, Baxter AG
 
ABSTRACT: The relative risk of type 1 (autoimmune) diabetes mellitus for a sibling of an affected patient is fifteen times that of the general population, indicating a strong genetic contrib...

366. (Journal Article): XIAP overexpression in human islets prevents early posttransplant apoptosis and reduces the islet mass needed to treat diabetes

Emamaullee JA, Rajotte RV, Liston P, Korneluk RG, Lakey JR, Shapiro AM, Elliott JF
 
ABSTRACT: The Edmonton Protocol for treatment of type 1 diabetes requires islets from two or more donors to achieve euglycemia in a single recipient, primarily because soon after portal infu...

367. (Journal Article): Imbalance in Th Cell Polarization and its Relevance in Type 1 Diabetes Mellitus

Sia C
 
ABSTRACT: Functional polarization of T helper (Th) subsets of lymphocytes has been implicated in promoting or conferring risk to Type 1 diabetes mellitus (T1DM) development in human and diab...

368. (Journal Article): Pancreatic duodenal homeobox-1, PDX-1, a major regulator of beta-cell identity and function.

Mckinnon CM, Docherty K
 
ABSTRACT: Pancreatic duodenal homeobox -1 is a transcription factor that is expressed in beta and delta cells of the islets of Langerhans and in dispersed endocrine cells of the duodenum. It...

369. (Journal Article): Insulin production by human embyronic stem cells.

Assady S, Maor G, Amit M, Itskovitz-Eldor J, Skorecki KL
 
ABSTRACT: Type 1 diabetes generally results from autoimmune destruction of pancreatic islet beta-cells, with consequent absolute insulin deficiency and complete dependence on exogenous insul...

370. (Journal Article): A Case of Acquired Generalized Lipodystrophy with Cerebellar Degeneration and Type 2 Diabetes Mellitus

Chao PJ, Tsai JCR, Chang DM, Shin SJ, Lee YJ
 
ABSTRACT: Acquired generalized lipodystrophy (AGL) is a rare disorder of adipose tissue characterized by loss of fat from large regions of the body, occurring after birth. Its etiology remai...