261. (Journal Article): Prediction and pathogenesis in type 1 diabetes

Ziegler AG, Nepom GT
 
ABSTRACT: A combination of genetic and immunological features is useful for prediction of autoimmune diabetes. Patterns of immune response correspond to the progression from a preclinical ph...

262. (Journal Article): Type 1 Diabetes and NKT Cells: A Report on the 3rd International Workshop on NKT Cells and CD1-Mediated Antigen Presentation, September 2004, Heron Island, QLD, Australia

Fletcher JM, Jordan MA, Baxter AG
 
ABSTRACT: NKT cells play a major role in regulating the vigor and character of a broad range of immune responses. Defects in NKT cell numbers and function have been associated with type 1 di...

263. (Journal Article): Approaches Towards Endogenous Pancreatic Regeneration

Banerjee M, Kanitkar M, Bhonde RR
 
ABSTRACT: The phenomenon of pancreatic regeneration in mammals has been well documented. It has been shown that pancreatic tissue is able to regenerate in several species of mammal after sur...

264. (Journal Article): Islet Generation from Intra Islet Precursor Cells of Diabetic Pancreas: In Vitro Studies Depicting In Vivo Differentiation

Banerjee M, Bhonde RR
 
ABSTRACT: CONTEXT: Beta-cells have a limited replicative capacity; hence, there is always a quest for sources of islet regeneration to compensate for the loss of functional beta-cells in dia...

265. (Journal Article): Cell replacement therapy for type 1 diabetes.

Efrat S
 
ABSTRACT: Replacement of the insulin-producing pancreatic islet beta cells represents the ultimate treatment for type 1 diabetes. Recent advances in islet transplantation underscore the urge...

266. (Journal Article): Elimination of Dietary Gluten and Development of Type 1 Diabetes in High Risk Subjects

Fuchtenbusch M, Ziegler AG, Hummel M
 
ABSTRACT: Removal of dietary gluten is associated with a lower frequency of type 1 diabetes (T1D) in patients with celiac disease. Therefore, we performed a pilot study in which seven islet-...

267. (Journal Article): Apoptosis in Autoimmune Diabetes: The Fate of β-Cells in the Cleft between Life and Death

Sia C, Hanninen A
 
ABSTRACT: Cytokine-induced β-cell death is the end-stage event in the pathogenesis of autoimmune diabetes. Beside cytokines, several pro-apoptotic pathways mediated through nitric oxide, re...

268. (Journal Article): Adult human cytokeratin 19-positive cells reexpress insulin promoter factor 1 in vitro.

Gmyr V, Kerr-Conte J, Belaich S, Vandewalle B, Leteurtre E, Vantyghem MC, Lecomte-Houcke M, Proye C, Lefebvre J, Pattou F
 
ABSTRACT: Human pancreatic cells with a typical ductal phenotype and potential to proliferate can be obtained in vitro, but the differentiation capacity of these putative human pancreatic st...

269. (Journal Article): Immunotherapy After Recent-Onset Type 1 Diabetes: Combinatorial Treatment for Achieving Long-Term Remission in Humans?

Bresson D, von Herrath M
 
ABSTRACT: Insulin-dependent diabetes mellitus (IDDM), or type 1 diabetes mellitus (TlDM), is one of the most common autoimmune diseases. This chronic disorder is thought to be caused by auto...

270. (Journal Article): Prospects for gene therapy of insulin-dependent diabetes mellitus.

Efrat S
 
ABSTRACT: The application of gene therapy to type I (insulin-dependent) diabetes mellitus awaits improvements in gene transfer technologies and the development of better tools for accurate d...