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21. (Journal Article): Growth and function of the embryonic heart depend upon the cardiac-specific L-type calcium channel alpha1 subunit.
Rottbauer W, Baker K, Wo ZG, Mohideen MA, Cantiello HF, Fishman MC ABSTRACT:
The heart must function from the moment of its embryonic assembly, but the molecular underpinnings of the first heart beat are not known, nor whether function determines form at th...
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Diabetes OD
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Diabetic Complicatio...
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Cardiovascular
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Calcium
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Calcium channel
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Journal Article
submitted: Oct 17, 2009 |
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22. (Journal Article): Sequence and expression of mRNAs encoding the alpha 1 and alpha 2 subunits of a DHP-sensitive calcium channel.
Ellis SB, Williams ME, Ways NR, Brenner R, Sharp AH, Leung AT, Campbell KP, McKenna E, Koch WJ, Hui A ABSTRACT:
Complementary DNAs were isolated and used to deduce the primary structures of the alpha 1 and alpha 2 subunits of the dihydropyridine-sensitive, voltage-dependent calcium channel f...
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Diabetes OD
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Diabetic Complicatio...
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Cardiovascular
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Calcium
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Calcium channel
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Journal Article
submitted: Oct 17, 2009 |
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23. (Journal Article): Normalization of glucose concen-trations and deceleration of gastric emptying after solid meals during intravenous glucagon-like peptide 1 in patients with type 2 diabetes.
Meier JJ, Gallwitz B, Salmen S, Goetze O, Holst JJ, Schmidt WE, Nauck MA ABSTRACT:
The effects of different i.v. doses of glucagon-like peptide 1 (GLP-1) on glucose homeostasis and gastric emptying were compared in patients with type 2 diabetes. Twelve patients w...
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Diabetes OD
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Reversal/Prevention ...
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T2DM
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Insulinotropic Subst...
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Incretins
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GLP-1
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Journal Article
submitted: Jun 13, 2006 |
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24. (Journal Article): Cell replacement therapy for type 1 diabetes.
Efrat S ABSTRACT:
Replacement of the insulin-producing pancreatic islet beta cells represents the ultimate treatment for type 1 diabetes. Recent advances in islet transplantation underscore the urge...
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Diabetes OD
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Regeneration of Isle...
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Stem Cells
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Other Cell Sources
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Progenitors
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Journal Article
submitted: Jun 13, 2006 |
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25. (Journal Article): Analysis of the VNTR locus D1S80 by the PCR fol-lowed by high-resolution PAGE.
Budowle B, Chakraborty R, Giusti AM, Eisenberg AJ, Allen RC ABSTRACT:
Allelic data for the D1S80 locus was obtained by using the PCR and subsequent analysis with a high-resolution, horizontal PAGE technique and silver staining. Compared with RFLP ana...
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Diabetes OD
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Diabetes Pathogenesi...
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T2DM
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Genetics
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Gene Discovery Appro...
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VNTR
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PAGE Anakysis
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Journal Article
submitted: Nov 30, 2005 |
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26. (Journal Article): Accelerated telomere shortening and senescence in human pancreatic islet cells stimulated to divide in vitro.
Halvorsen TL, Beattie GM, Lopez AD, Hayek A, Levine F ABSTRACT:
Widespread application of beta-cell replacement strategies for diabetes is dependent upon the availability of an unlimited supply of cells exhibiting appropriate glucose-responsive...
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Diabetes OD
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Regeneration of Isle...
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Stem Cells
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Isolated Islet Cells
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Stimulation of Divis...
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Journal Article
submitted: Apr 06, 2006 |
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27. (Journal Article): Pancreatic Pseudocysts Following Acute Pancreatitis: Risk Factors Influencing Therapeutic Outcomes
Soliani P, Franzini C, Ziegler S, Del Rio P, Dell'Abate P, Piccolo D, Japichino GG, Cavestro GM, Di Mario F, Sianesi M ABSTRACT:
CONTEXT: The natural history of pancreatic pseudocysts has become well known in recent years, but the choice of a proper treatment still remains controversial. OBJECTIVE: This stud...
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Diabetes OD
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Journals
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JOP
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2004
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Journal Article
submitted: Jun 13, 2006 |
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28. (Journal Article): C-peptide enhances insulin-mediated cell growth and protection against high glucose induced apoptosis in SH-SY5Y cells.
Li Z-G, Zhang W, Sima AAF ABSTRACT:
BACKGROUND: We have previously reported that C-peptide exerts preventive and therapeutic effects on diabetic neuropathy in type 1 diabetic BB/Wor-rats and that it prevents duration...
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Diabetes OD
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Diabetic Complicatio...
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Neural
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Journal Article
submitted: Jun 13, 2006 |
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29. (Journal Article): TNF-alpha acts to prevent occurrence of malformed fetuses in diabetic mice.
Torchinsky A, Gongadze M, Orenstein H, Savion S, Fein A, Toder V ABSTRACT:
AIMS/HYPOTHESIS: Activation of apoptosis in embryos is thought to be a key event in the pathogenesis of diabetes-induced embryopathies such as early embryonic death and inborn stru...
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Diabetes OD
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Diabetic Complicatio...
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Risk of Diabetes
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Diabetic Embryopathy...
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Malformation
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Protection by TNF-al...
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Journal Article
submitted: Jun 13, 2006 |
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30. (Journal Article): Diabetes-Induced Fetal Growth Retardation is Associated with Suppression of NF-κB Activity in Embryos
Mammon K, Keshet R, Savion S, Pekar O, Zaslavsky Z, Fein A, Toder V, Torchinsky A ABSTRACT:
BACKGROUND: Mechanisms underlying diabetes-induced fetal growth retardation remain largely undefined. Two events such as the persistent activation of apoptosis or suppression of ce...
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Diabetes OD
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Diabetic Complicatio...
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Risk of Diabetes
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Diabetic Embryopathy...
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Retardation
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Disturbances in Prot...
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NF-κB Expressio...
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Journal Article
submitted: Jun 13, 2006 |
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