191. (Journal Article): Manganese Superoxide Dismutase Alanine to Valine Polymorphism and Risk of Neuropathy and Nephropathy in Egyptian Type 1 Diabetic Patients

El Masry TM, Abou Zahra MA, El Tawil MM, Khalifa RA
 
ABSTRACT: Oxidative stress, characterized by a marked increase in the level of oxygen free radicals (OFR), has been implicated in the development of diabetic microangiopathic complications, ...

192. (Journal Article): Approaches Towards Endogenous Pancreatic Regeneration

Banerjee M, Kanitkar M, Bhonde RR
 
ABSTRACT: The phenomenon of pancreatic regeneration in mammals has been well documented. It has been shown that pancreatic tissue is able to regenerate in several species of mammal after sur...

193. (Journal Article): Gastric inhibitory polypeptide: the neglected incretin revisited.

Meier JJ, Nauck MA, Schmidt WE, Gallwitz B
 
ABSTRACT: After the ingestion of fat- and glucose-rich meals, gut hormones are secreted into the circulation in order to stimulate insulin secretion. This so-called "incretin effect&quo...

194. (Journal Article): Use of transgenic mice to study voltage-dependent Ca2+ channels.

Muth JN, Varadi G, Schwartz A
 
ABSTRACT: During the past decade a great number of genes encoding high- and low-voltage-dependent Ca(2+) channels and their accessory subunits have been cloned. Studies of Ca(2+) channel str...

195. (Journal Article): Pancreas preservation by the two layer cold storage method before islet isolation protects isolated islets against apoptosis through the mitochondrial pathway.

Matsuda T, Suzuki Y, Tanioka Y, Toyama H, Kakinoki K, Hiraoka K, Fujino Y, Kuroda Y
 
ABSTRACT: BACKGROUND: Apoptosis in isolated islets has been implicated in primary nonfunction or early graft failure after islet transplantation. Recently, pancreas preservation by the 2-lay...

196. (Journal Article): Phosphatidylinositol 3-kinase signaling to Akt mediates survival in isolated canine islets of Langerhans.

Aikin R, Rosenberg L, Maysinger D
 
ABSTRACT: The isolation of islet cells from the pancreas by enzymatic digestion causes many of these cells to undergo apoptosis. The aim of this work was to investigate the role of phosphati...

197. (Journal Article): Synthesis and differentially regulated processing of proinsulin in developing chick pancreas, liver and neuroretina.

Alarcon C, Serna J, Perez-Villamil B, de Pablo F
 
ABSTRACT: Regulated preproinsulin gene expression in nonpancreatic tissues during development has been demonstrated in rodents, Xenopus and chicken. Little is known, however, about the synth...

198. (Journal Article): Origin of exocrine pancreatic cells from nestin-positive precursors in developing mouse pancreas.

Esni F, Stoffers DA, Takeuchi T, Leach SD
 
ABSTRACT: During pancreatic development, endocrine and exocrine cell types arise from common precursors in foregut endoderm. However, little information is available regarding regulation of ...

199. (Journal Article): Morphology and function of cultured human fetal pancreatic cells transplanted into athymic mice: a longitudinal study.

Beattie GM, Butler C, Hayek A
 
ABSTRACT: Islet-like cell clusters generated from human fetal pancreases between 18-24 wk gestation were able to grow and mature both morphologically and functionally after transplantation u...

200. (Journal Article): Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets

Lumelsky N, Blondel O, Laeng P, Velasco I, Ravin R, McKay R
 
ABSTRACT: Although the source of embryonic stem (ES) cells presents ethical concerns, their use may lead to many clinical benefits if differentiated cell types can be derived from them and u...