181. (Journal Article): Ethnicity and cardiovascular disease. The incidence of myocardial infarction in white, South Asian, and Afro-Caribbean patients with type 2 diabetes (U.K. Prospective Diabetes Study 32)

No indication of authors
 
ABSTRACT: OBJECTIVE: To estimate the incidence of myocardial infarction (MI) by ethnicity in subjects with diabetes and to examine the effect of ethnicity, adjusting for differences in cardi...

182. (Journal Article): Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells.

Jonuleit H, Schmitt E, Schuler G, Knop J, Enk AH
 
ABSTRACT: The functional properties of dendritic cells (DCs) are strictly dependent on their maturational state. To analyze the influence of the maturational state of DCs on priming and diff...

183. (Journal Article): Calmodulin-induced early-onset diabetes in transgenic mice.

Epstein PN, Overbeek PA, Means AR
 
ABSTRACT: Calmodulin is implicated as the primary transducer of the calcium signal in pancreatic beta cells, where it is present at very high concentrations. We have produced three lines of ...

184. (Journal Article): Pathogen-specific regulatory T cells provoke a shift in the Th1/Th2 paradigm in immunity to infectious diseases.

McGuirk P, Mills KH
 
ABSTRACT: Current dogma suggests that immunity to infection is controlled by distinct type 1 (Th1) and type 2 (Th2) subpopulations of T cells discriminated on the basis of cytokine secretion...

185. (Information): Operating Guidelines and Conditions of Use for Editors of the Diabetes Open Directory - DOD

Info SBDR
 
ABSTRACT: n.a.

186. (Journal Article): Structural and functional analysis of the costimulatory receptor programmed death-1.

Zhang X, Schwartz JC, Guo X, Bhatia S, Cao E, Lorenz M, Cammer M, Chen L, Zhang ZY, Edidin MA, Nathenson SG, Almo SC
 
ABSTRACT: PD-1, a member of the CD28/CTLA-4/ICOS costimulatory receptor family, delivers negative signals that have profound effects on T and B cell immunity. The 2.0 A crystal structure of ...

187. (Journal Article): Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor.

Nishimura H, Nose M, Hiai H, Minato N, Honjo T
 
ABSTRACT: PD-1, a 55 kDa transmembrane protein containing an immunoreceptor tyrosine-based inhibitory motif, is induced in lymphocytes and monocytic cells following activation. Aged C57BL/6(...

188. (Journal Article): The Association of Silent Coronary Artery Disease and Metabolic Syndrome in Chinese with Type 2 Diabetes Mellitus

Tsai JCR, Chang DM, Chung FM, Wu JC, Shin SJ, Lee YJ
 
ABSTRACT: OBJECTIVES: Cardiovascular diseases account for approximately 75% of the deaths that occur in patients with diabetes. Because the clinical signs of coronary artery disease (CAD) in...

189. (Journal Article): Prediction and pathogenesis in type 1 diabetes

Ziegler AG, Nepom GT
 
ABSTRACT: A combination of genetic and immunological features is useful for prediction of autoimmune diabetes. Patterns of immune response correspond to the progression from a preclinical ph...

190. (Journal Article): Approaches Towards Endogenous Pancreatic Regeneration

Banerjee M, Kanitkar M, Bhonde RR
 
ABSTRACT: The phenomenon of pancreatic regeneration in mammals has been well documented. It has been shown that pancreatic tissue is able to regenerate in several species of mammal after sur...