141. (Journal Article): Analysis of parent-offspring trios provides evidence for linkage and association between the insulin gene and type 2 diabetes mediated exclusively through paternally transmitted class III variable number tandem repeat alleles

Huxtable SJ, Saker PJ, Haddad L, Walker M, Frayling TM, Levy JC, Hitman GA, O'Rahilly S, Hattersley AT, McCarthy MI
 
ABSTRACT: Variation at the variable number tandem repeat (VNTR) minisatellite 5' of the insulin gene (INS) is associated with several phenotypes, including type 1 diabetes, polycystic ovary ...

142. (Journal Article): Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos.

Sanes JR, Rubenstein JL, Nicolas JF
 
ABSTRACT: We show that a gene introduced into cells of mouse embryos by a retrovirus can serve as a heritable marker for the study of cell lineage in vivo. We constructed a defective recombi...

143. (Journal Article): Preservation of human islet cell functional mass by anti-oxidative action of a novel SOD mimic compound.

Bottino R, Balamurugan AN, Bertera S, Pietropaolo M, Trucco M, Piganelli JD
 
ABSTRACT: The most commonly used technical approach to isolate human pancreatic islets intended for allotransplants generates a product that is hampered by mechanical and chemical insults, w...

144. (Journal Article): Adenoviral gene transfer of erythropoietin confers cytoprotection to isolated pancreatic islets.

Fenjves ES, Ochoa MS, Gay-Rabinstein C, Molano RD, Pileggi A, Mendez AJ, Inverardi L, Ricordi C
 
ABSTRACT: BACKGROUND: The transfer of cytoprotective genes to isolated pancreatic islets may contribute to their enhanced survival in the transplant setting. Our laboratory established the e...

145. (Journal Article): Lentivirus-mediated Bcl-2 expression in betaTC-tet cells improves resistance to hypoxia and cytokine-induced apoptosis while preserving in vitro and in vivo control of insulin secretion.

Dupraz P, Rinsch C, Pralong WF, Rolland E, Zufferey R, Trono D, Thorens B
 
ABSTRACT: betaTC-tet cells are conditionally immortalized pancreatic beta cells which can confer long-term correction of hyperglycemia when transplanted in syngeneic streptozocin diabetic mi...

146. (Journal Article): Microvascular Complications in Cystic Fibrosis-Related Diabetes Mellitus: a Case Report.

Scott AIR, Clarke BE, Healy H, D'Emden M, Bell SC
 
ABSTRACT: CONTEXT, The prevalence of cystic fibrosis-related diabetes mellitus is increasing and is associated with increased survival from cystic fibrosis. CASE REPORT, This study describes...

147. (Journal Article): Trypsin Activation Peptide (TAP) in Acute Pancreatitis: From Pathophysiology to Clinical Usefulness

Frossard JL

148. (Journal Article): The Impact on Clinical Practice of Endoscopic Ultrasonography Used for the Diagnosis and Staging of Pancreatic Adenocarcinoma

Queneau PE, Sauvé G, Koch S, Thibault P, Cléau D, Heyd B, Mantion G, Carayon P
 
ABSTRACT: CONTEXT: Endoscopic ultrasonography is considered a highly accurate procedure for diagnosing small pancreatic tumors and assessing their locoregional extension. OBJECTIVE: To evalu...

149. (Journal Article): Jejunal Feeding in Chronic Pancreatitis with Severe Necrosis

Hamvas J, Schwab R, Pap á
 
ABSTRACT: CONTEXT: Necrotizing pancreatitis is the most serious form of pancreatic inflammatory disease leading to multiorgan failure and a high (15-20%) mortality rate. The poor nutritional...

150. (Journal Article): A is for Amylin and Amyloid in Type 2 Diabetes Mellitus

Hayden MR, Tyagi SC
 
ABSTRACT: Amyloid deposits within the islet of the pancreas have been known for a century. In 1987, the islet amyloid precursor polypeptide (IAPP) amylin (a 37 amino acid) was discovered. Re...