31. (Journal Article): Association between Ala-9Val polymorphism of Mn-SOD gene and schizophrenia.

Akyol O, Yanik M, Elyas H, Namli M, Canatan H, Akin H, Yuce H, Yilmaz HR, Tutkun H, Sogut S, Herken H, Ozyurt H, Savas HA, Zoroglu SS
 
ABSTRACT: Reactive oxygen species (ROS) have been suggested to play an important role in physiopathology of schizophrenia. The major intracellular antioxidant enzymes, copper-zinc superoxide...

32. (Journal Article): Analysis of mitochondrial targeting sequence and coding region polymorphisms of the manganese superox-ide dismutase gene in German Parkinson disease patients.

Grasbon-Frodl EM, Kosel S, Riess O, Muller U, Mehraein P, Graeber MB
 
ABSTRACT: Two polymorphisms of the MnSOD gene, Ile58Thr and Ala9Val, have been associated with Parkinson disease (PD). The Ile58Thr amino acid exchange affects the stability at the tetrameri...

33. (Journal Article): Analysis of the VNTR locus D1S80 by the PCR fol-lowed by high-resolution PAGE.

Budowle B, Chakraborty R, Giusti AM, Eisenberg AJ, Allen RC
 
ABSTRACT: Allelic data for the D1S80 locus was obtained by using the PCR and subsequent analysis with a high-resolution, horizontal PAGE technique and silver staining. Compared with RFLP ana...

34. (Journal Article): Early glycemic control, age at onset, and development of microvascular complications in childhood-onset type 1 diabetes: a population-based study in northern Sweden.

Svensson M, Eriksson JW, Dahlquist G
 
ABSTRACT: OBJECTIVE: The aim of this work was to study the impact of glycemic control (HbA(1c)) early in disease and age at onset on the occurrence of incipient diabetic nephropathy (MA) and...

35. (Journal Article): Pancreatic Pseudocysts Following Acute Pancreatitis: Risk Factors Influencing Therapeutic Outcomes

Soliani P, Franzini C, Ziegler S, Del Rio P, Dell'Abate P, Piccolo D, Japichino GG, Cavestro GM, Di Mario F, Sianesi M
 
ABSTRACT: CONTEXT: The natural history of pancreatic pseudocysts has become well known in recent years, but the choice of a proper treatment still remains controversial. OBJECTIVE: This stud...

36. (Journal Article): Remission in models of type 1 diabetes by gene therapy using a single chain insulin-analogue.

Lee HC, Kim SJ, Kim KS, Shin HC, Yoon JW
 
ABSTRACT: A cure for diabetes has long been sought using several different approaches, including islet transplantation, regeneration of beta cells and insulin gene therapy. However, permanen...

37. (Journal Article): C-peptide enhances insulin-mediated cell growth and protection against high glucose induced apoptosis in SH-SY5Y cells.

Li Z-G, Zhang W, Sima AAF
 
ABSTRACT: BACKGROUND: We have previously reported that C-peptide exerts preventive and therapeutic effects on diabetic neuropathy in type 1 diabetic BB/Wor-rats and that it prevents duration...

38. (Journal Article): TNF-alpha acts to prevent occurrence of malformed fetuses in diabetic mice.

Torchinsky A, Gongadze M, Orenstein H, Savion S, Fein A, Toder V
 
ABSTRACT: AIMS/HYPOTHESIS: Activation of apoptosis in embryos is thought to be a key event in the pathogenesis of diabetes-induced embryopathies such as early embryonic death and inborn stru...

39. (Journal Article): In vivo evidence for the existence of a threshold for hyperglycemia-induced major fetal malformations: relevance to the etiology of diabetic teratogenesis.

Torchinsky A, Toder V, Carp H, Orenstein H, Fein A
 
ABSTRACT: The present study was carried out to evaluate whether hyperglycemia-induced major fetal anomalies are thresholded phenomena. Streptozotocin (STZ)-treated female ICR mice were exami...

40. (Journal Article): Diabetes-Induced Fetal Growth Retardation is Associated with Suppression of NF-κB Activity in Embryos

Mammon K, Keshet R, Savion S, Pekar O, Zaslavsky Z, Fein A, Toder V, Torchinsky A
 
ABSTRACT: BACKGROUND: Mechanisms underlying diabetes-induced fetal growth retardation remain largely undefined. Two events such as the persistent activation of apoptosis or suppression of ce...