11. (Journal Article): Beginning at the end with SUMO.

Matunis MJ, Pickart CM
 
ABSTRACT: The crystal structure of a four-protein complex comprising a SUMO ligase (E3), a SUMOylated protein substrate, and the cognate SUMO-conjugating enzyme sheds new light on catalysis,...

12. (Journal Article): NF-kappaB at the crossroads of life and death.

Karin M, Lin A
 
ABSTRACT: The choice between life and death is one of the major events in regulation of the immune system. T cells that specifically recognize viral or bacterial antigens are selected to sur...

13. (Journal Article): Foxp3 programs the development and function of CD4+CD25+ regulatory T cells.

Fontenot JD, Gavin MA, Rudensky AY
 
ABSTRACT: CD4+CD25+ regulatory T cells are essential for the active suppression of autoimmunity. Here we report that the forkhead transcription factor Foxp3 is specifically expressed in CD4+...

14. (Journal Article): Pancreatic and intestinal processing of proglucagon in man.

0rskov C, Holst JJ, Poulsen S, Kirkegaard P
 
ABSTRACT: We developed antisera and radioimmunoassays against synthetic replicas of glucagon-like peptide-1 (1-36) and -2, predicted products of the glucagon precursor, and against glucagon-...

15. (Journal Article): NeuroD-betacellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in mice.

Kojima H, Fujimiya M, Matsumura K, Younan P, Imaeda H, Maeda M, Chan L
 
ABSTRACT: To explore induced islet neogenesis in the liver as a strategy for the treatment of diabetes, we used helper-dependent adenovirus (HDAD) to deliver the pancreatic duodenal homeobox...

16. (Journal Article): Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers.

Itskovitz-Eldor J, Schuldiner M, Karsenti D, Eden A, Yanuka O, Amit M, Soreq H, Benvenisty N
 
ABSTRACT: BACKGROUND: Embryonic stem (ES) cells are lines of cells that are isolated from blastocysts. The murine ES cells were demonstrated to be true pluripotent cells as they differentiat...

17. (Journal Article): PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum.

Offield MF, Jetton TL, Labosky PA, Ray M, Stein RW, Magnuson MA, Hogan BL, Wright CVE
 
ABSTRACT: It has been proposed that the Xenopus homeobox gene, XlHbox8, is involved in endodermal differentiation during pancreatic and duodenal development (Wright, C.V.E., Schnegelsberg, P...

18. (Journal Article): Novel Insights in the Regulation of the Immune System: A Report on the FASEB Summer Research Conference on Autoimmunity, 2003

Gronski MA
 
ABSTRACT: The bi-annual FASEB autoimmunity conference organized last year by Betty Diamond and Stephen Miller brought together some 150 delegates studying various aspects of autoimmune disea...

19. (Journal Article): Making sense of glucose sensing.

Efrat S
 
ABSTRACT: n.a.

20. (Journal Article): Biochemistry and molecular cell biology of diabetic complications.

Brownlee M