1. (Journal Article): Making sense of glucose sensing.

Efrat S
 
ABSTRACT: n.a.

2. (Journal Article): Biochemistry and molecular cell biology of diabetic complications.

Brownlee M

3. (Journal Article): Assessing the validity of the association be-tween the SUMO4 M55V variant and risk of type 1 diabetes.

Smyth DJ, Howson JM, Lowe CE, Walker NM, Lam AC, Nutland S, Hutchings J, Tuomilehto-Wolf E, Tuomilehto J, Guja C, Ionescu-Tirgoviste C, Undlien DE, Ronningen KS, Savage D, Dunger DB, Twells RC, McArdle WL, Strachan DP, Todd JA.
 
ABSTRACT: Not available.

4. (Journal Article): Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus

Horikawa Y, Oda N, Cox NJ, Li X, Orho-Melander M, Hara M, Hinokio Y, Lindner TH, Mashima H, Schwarz PE, del Bosque-Plata L, Horikawa Y, Oda Y, Yoshiuchi I, Colilla S, Polonsky KS, Wei S, Concannon P, Iwasaki N, Schulze J, Baier LJ, Bogardus C, Groop L, Boerwinkle E, Hanis CL, Bell GI
 
ABSTRACT: Type 2 or non-insulin-dependent diabetes mellitus (NIDDM) is the most common form of diabetes worldwide, affecting approximately 4% of the world's adult population. It is multifact...

5. (Journal Article): Beginning at the end with SUMO.

Matunis MJ, Pickart CM
 
ABSTRACT: The crystal structure of a four-protein complex comprising a SUMO ligase (E3), a SUMOylated protein substrate, and the cognate SUMO-conjugating enzyme sheds new light on catalysis,...

6. (Journal Article): Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B.

Beg AA, Sha WC, Bronson RT, Ghosh S, Baltimore D
 
ABSTRACT: NF-kappa B, which consists of two polypeptides, p50 (M(r) 50K) and p65/RelA (M(r) 65K), is thought to be a key regulator of genes involved in responses to infection, inflammation a...

7. (Journal Article): The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3.

Bennett CL, Christie J, Ramsdell F, Brunkow ME, Ferguson PJ, Whitesell L, Kelly TE, Saulsbury FT, Chance PF, Ochs HD
 
ABSTRACT: IPEX is a fatal disorder characterized by immune dysregulation, polyendocrinopathy, enteropathy and X-linked inheritance (MIM 304930). We present genetic evidence that different mu...

8. (Journal Article): Functional variants in SUMO4, TAB2, and NFkappaB and the risk of type 1 diabetes.

Kosoy R, Concannon P
 
ABSTRACT: Several functional genetic variants that can potentially modulate the activity of NFkappaB have been recently described. As reduced NFkappaB activity has been implicated in risk fo...

9. (Journal Article): SUMO: a regulator of gene expression and genome integrity.

Muller S, Ledl A, Schmidt D
 
ABSTRACT: Post-translational modification with the ubiquitin-like SUMO protein is involved in the regulation of many cellular key processes. The SUMO system modulates signal transduction pat...

10. (Journal Article): NFkappaB polymorphisms and susceptibility to type 1 diabetes.

Hegazy DM, O'Reilly DA, Yang BM, Hodgkinson AD, Millward BA, Demaine AG
 
ABSTRACT: Nuclear factor kappa B (NFkappaB) is an important transcription factor that is involved in the response to oxidative stress and inflammation. Recent studies suggest that it may be ...