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21. (Journal Article): Nestin-positive progenitor cells derived from adult human pancreatic islets of Langerhans contain side population (SP) cells defined by expression of the ABCG2 (BCRP1) ATP-binding cassette transporter.
Lechner A, Leech CA, Abraham EJ, Nolan AL, Habener JF ABSTRACT:
The disease diabetes mellitus arises as a consequence of a failure of the beta-cells in the islets of Langerhans of the pancreas to produce insulin in the amounts required to meet ...
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Diabetes OD
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Regeneration of Isle...
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Stem Cells
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Other Cell Sources
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Progenitors
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Derived from Adult I...
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Journal Article
submitted: Oct 31, 2006 |
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22. (Journal Article): The efficacy of Silybum marianum (L.) Gaertn. (silymarin) in the treatment of type II diabetes: a randomized, double-blind, placebo-controlled, clinical trial.
Huseini HF, Larijani B, Heshmat R, Fakhrzadeh H, Radjabipour B, Toliat T, Raza M. ABSTRACT:
Oxidative stresses are increasingly implicated in the pathogenesis of diabetic complications which may either cause direct pancreatic beta-cell damage or lead to metabolic abnormal...
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Diabetes OD
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Disease Management
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T2DM
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Complementary Therap...
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Journal Article
submitted: Nov 08, 2006 |
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23. (Journal Article): Low-Protein Vegetarian Diet with Alpha-Chetoanalogues Prior to Pre-emptive Pancreas-Kidney Transplantation
Piccoli GB, Motta D, Martina G, Consiglio V, Gai M, Mezza E, Maddalena E, Burdese M, Colla L, Tattoli F, Anania P, Rossetti M, Soragna G, Grassi G, Dani F, Jeantet A, Segoloni GP ABSTRACT:
BACKGROUND: Pre-emptive pancreas-kidney transplantation is increasingly considered the best therapy for irreversible chronic kidney disease (CKD) in type 1 diabetics. However, the ...
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Diabetes OD
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Diabetic Complicatio...
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Renal
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Transplantation
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Kidney-Pancreas Tran...
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Journal Article
submitted: Jun 13, 2006 |
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24. (Journal Article): "Low Dose" Metformin Improves Hyperglycemia Better Than Acarbose in Type 2 Diabetics
Yajima K, Shimada A, Hirose H, Kasuga A, Saruta T ABSTRACT:
OBJECTIVES: "High dose" metformin therapy (2,550 mg/day) is reported to improve glycemic control in type 2 diabetic patients with obesity (body mass index (BMI) >= 30)...
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Diabetes OD
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Disease Management
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Metabolic Control
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Journal Article
submitted: Jun 13, 2006 |
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25. (Journal Article): Transcribing pancreas.
Edlund H ABSTRACT:
For approximately 30-35 years, our insight into some of the fundamental aspects of pancreas development has been based mainly on two independent studies performed in the 1960s by G...
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Diabetes OD
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Development and Func...
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Pancreas
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Gene Activation and ...
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Transcription Factor...
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Journal Article
submitted: Apr 05, 2006 |
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26. (Journal Article): Diabetes mellitus: report of a WHO study group. WHO, Geneva.
World Health Organization ABSTRACT:
n/a
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Diabetes OD
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Reversal/Prevention ...
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T1DM
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Journal Article
submitted: Apr 25, 2007 |
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27. (Journal Article): The role of GLP-1 in the life and death of pancreatic beta cells.
Perfetti R, Hui H ABSTRACT:
Glucagon-like peptide-1 (GLP-1), a peptide hormone produce by intestinal cells, has recently been shown to be capable of modulating islet cell mass. Administration of GLP-1 to rode...
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Diabetes OD
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Regeneration of Isle...
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Stem Cells
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Other Cell Sources
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Replication
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Incretin hormones
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GLP-1
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Journal Article
submitted: Nov 19, 2005 |
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28. (Journal Article): The Application of Umbilical Cord Blood Cells in the Treatment of Diabetes Mellitus
Koblas T, Harman SM, Saudek F ABSTRACT:
In recent years, human umbilical cord blood (HUCB) has emerged as an attractive tool for cell-based therapy. Although at present the clinical application of HUCB is limited to the ...
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Diabetes OD
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Regeneration of Isle...
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Stem Cells
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Other Cell Sources
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Umbilical Cord Blood
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Journal Article
submitted: Oct 03, 2006 |
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29. (Journal Article): Functional variants in SUMO4, TAB2, and NFkappaB and the risk of type 1 diabetes.
Kosoy R, Concannon P ABSTRACT:
Several functional genetic variants that can potentially modulate the activity of NFkappaB have been recently described. As reduced NFkappaB activity has been implicated in risk fo...
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Diabetes OD
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Diabetes Pathogenesi...
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T1DM
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Autoimmunity
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Genetics of Autoimmu...
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SUMO4
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Polymorphism
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Journal Article
submitted: Aug 24, 2005 |
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30. (Journal Article): Characterization of a nuclear-factor-kappa B (NFkappaB) genetic marker in type 1 diabetes (T1DM) families.
Gylvin T, Bergholdt R, Nerup J, Pociot F ABSTRACT:
Cytokine-induced beta-cell death is an important factor in the pathogenesis of type 1 diabetes mellitus (T1DM). The transcription factor NFkappaB plays an important role in cytokin...
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Diabetes OD
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Diabetes Pathogenesi...
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T1DM
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Autoimmunity
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Genetics of Autoimmu...
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Immune Response Medi...
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NF-κB
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Journal Article
submitted: Aug 24, 2005 |
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