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11. (Journal Article): Glucagon-like peptide I analogues: effects on insulin secretion and adenosine 3',5'-monophosphate formation.
Gefel D, Hendrick GK, Mojsov S, Habener J, Weir GE ABSTRACT:
Glucagon-like peptide 1-(7-37) [GLP-I-(7-37)] is a 31-amino acid hormone which may have an important role in the regulation of insulin secretion, It is processed from preproglucago...
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Diabetes OD
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Development and Func...
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Pancreas
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Incretin Hormones
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GLP-1
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Journal Article
submitted: Nov 24, 2005 |
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12. (Journal Article): Increased Transcriptional Preproinsulin II Beta-Cell Activity in Neonatal Nonobese Diabetic Mice: In Situ Hybridization Analysis
Throsby M, Coulaud J, Durant S, Homo-Delarche F ABSTRACT:
In the prediabetic nonobese diabetic (NOD) mouse, a spontaneous model of type 1 diabetes, we previously reported transient postweaning hyperinsulinemia followed by progressive isle...
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Diabetes OD
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Diabetes Pathogenesi...
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T1DM
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Autoimmunity
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NOD mouse
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Hyperinsulinemia
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Journal Article
submitted: Jun 13, 2006 |
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13. (Journal Article): Novel Insights in the Regulation of the Immune System: A Report on the FASEB Summer Research Conference on Autoimmunity, 2003
Gronski MA ABSTRACT:
The bi-annual FASEB autoimmunity conference organized last year by Betty Diamond and Stephen Miller brought together some 150 delegates studying various aspects of autoimmune disea...
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Diabetes OD
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Development and Func...
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Immune System
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T Cells
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Regulatory T Cells
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Journal Article
submitted: Jun 13, 2006 |
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14. (Journal Article): Regeneration of pancreatic beta cells from intra-islet precursor cells in an experimental model of diabetes.
Guz Y, Nasir I, Teitelman G ABSTRACT:
We previously reported that new beta cells differentiated in pancreatic islets of mice in which diabetes was produced by injection of a high dose of the beta cell toxin streptozoto...
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Diabetes OD
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Regeneration of Isle...
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Neogenesis
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Endogenous Pancreati...
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Journal Article
submitted: Oct 31, 2006 |
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15. (Journal Article): Nestin-positive progenitor cells derived from adult human pancreatic islets of Langerhans contain side population (SP) cells defined by expression of the ABCG2 (BCRP1) ATP-binding cassette transporter.
Lechner A, Leech CA, Abraham EJ, Nolan AL, Habener JF ABSTRACT:
The disease diabetes mellitus arises as a consequence of a failure of the beta-cells in the islets of Langerhans of the pancreas to produce insulin in the amounts required to meet ...
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Diabetes OD
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Regeneration of Isle...
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Stem Cells
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Other Cell Sources
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Progenitors
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Derived from Adult I...
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Journal Article
submitted: Oct 31, 2006 |
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16. (Journal Article): The efficacy of Silybum marianum (L.) Gaertn. (silymarin) in the treatment of type II diabetes: a randomized, double-blind, placebo-controlled, clinical trial.
Huseini HF, Larijani B, Heshmat R, Fakhrzadeh H, Radjabipour B, Toliat T, Raza M. ABSTRACT:
Oxidative stresses are increasingly implicated in the pathogenesis of diabetic complications which may either cause direct pancreatic beta-cell damage or lead to metabolic abnormal...
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Diabetes OD
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Disease Management
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T2DM
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Complementary Therap...
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Journal Article
submitted: Nov 08, 2006 |
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17. (Journal Article): "Low Dose" Metformin Improves Hyperglycemia Better Than Acarbose in Type 2 Diabetics
Yajima K, Shimada A, Hirose H, Kasuga A, Saruta T ABSTRACT:
OBJECTIVES: "High dose" metformin therapy (2,550 mg/day) is reported to improve glycemic control in type 2 diabetic patients with obesity (body mass index (BMI) >= 30)...
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Diabetes OD
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Disease Management
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Metabolic Control
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Journal Article
submitted: Jun 13, 2006 |
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18. (Journal Article): Transcribing pancreas.
Edlund H ABSTRACT:
For approximately 30-35 years, our insight into some of the fundamental aspects of pancreas development has been based mainly on two independent studies performed in the 1960s by G...
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Diabetes OD
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Development and Func...
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Pancreas
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Gene Activation and ...
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Transcription Factor...
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Journal Article
submitted: Apr 05, 2006 |
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19. (Journal Article): Diabetes mellitus: report of a WHO study group. WHO, Geneva.
World Health Organization ABSTRACT:
n/a
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Diabetes OD
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Reversal/Prevention ...
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T1DM
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Journal Article
submitted: Apr 25, 2007 |
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20. (Journal Article): The role of GLP-1 in the life and death of pancreatic beta cells.
Perfetti R, Hui H ABSTRACT:
Glucagon-like peptide-1 (GLP-1), a peptide hormone produce by intestinal cells, has recently been shown to be capable of modulating islet cell mass. Administration of GLP-1 to rode...
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Diabetes OD
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Regeneration of Isle...
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Stem Cells
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Other Cell Sources
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Replication
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Incretin hormones
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GLP-1
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Journal Article
submitted: Nov 19, 2005 |
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