31. (Journal Article): Reversal of lesions of diabetic nephropathy after pancreas transplantation.

Fioretto P, Steffes MW, Sutherland DE, Goetz FC, Mauer M
 
ABSTRACT: BACKGROUND: In patients with type I diabetes mellitus who do not have uremia and have not received a kidney transplant, pancreas transplantation does not ameliorate established les...

32. (Journal Article): Pancreatic duodenal homeobox-1 and islet neogenesis associated protein: a possible combined marker of activateable pancreatic cell precursors.

Gagliardino JJ, Del Zotto H, Massa L, Flores LE, Borelli MI
 
ABSTRACT: The aim of this work was to study the possible relationship between pancreatic duodenal homeobox-1 (Pdx-1) and islet neogenesis-associated protein (INGAP) during induced islet neog...

33. (Journal Article): Prevalence of Type 2 Diabetic Patients Within the Targets of Care Guidelines in Daily Clinical Practice: A Multi-Center Study in Brazil

Gomes MB, Gianella D, Faria M, Tambascia M, Fonseca RM, Rea R, Macedo G, Filho JM, Schmid H, Bittencourt AV, Cavalcanti S, Rassi N, Pedrosa H, Dib SA
 
ABSTRACT: Major clinical studies have shown that the targets for blood glucose, lipid profile and blood pressure in type 2 diabetic patients are difficult to maintain in clinical practice. H...

34. (Journal Article): Cerebellar ataxia, seizures, premature death, and cardiac abnormalities in mice with targeted disruption of the Cacna2d2 gene.

Ivanov SV, Ward JM, Tessarollo L, McAreavey D, Sachdev V, Fananapazir L, Banks MK, Morris N, Djurickovic D, Devor-Henneman DE, Wei MH, Alvord GW, Gao B, Richardson JA, Minna JD, Rogawski MA, Lerman MI
 
ABSTRACT: CACNA2D2 is a putative tumor suppressor gene located in the human chromosome 3p21.3 region that shows frequent allelic imbalances in lung, breast, and other cancers. The alpha2delt...

35. (Journal Article): Mucosal Tolerance to Prevent Type 1 Diabetes: Can the Outcome Be Improved in Humans?

Hanninen A, Harrison LC
 
ABSTRACT: The results of trials in which autoantigens have been fed to individuals affected by autoimmune diseases - multiple sclerosis, rheumatoid arthritis and type 1 diabetes - have been ...

36. (Journal Article): Analysis and Optimization of Nutritional Set-up for Murine Pancreatic Acinar Cells.

Kurup S, Bhonde RR
 
ABSTRACT: CONTEXT: Pancreatic acinar cell cultivation poses a serious problem due to limitations in the in vitro survival time despite variations of dissociation protocols, culture media and...

37. (Journal Article): Islet Generation from Intra Islet Precursor Cells of Diabetic Pancreas: In Vitro Studies Depicting In Vivo Differentiation

Banerjee M, Bhonde RR
 
ABSTRACT: CONTEXT: Beta-cells have a limited replicative capacity; hence, there is always a quest for sources of islet regeneration to compensate for the loss of functional beta-cells in dia...

38. (Journal Article): Shell-Less Chick Embryo Culture as an Alternative in vitro Model to Investigate Glucose-Induced Malformations in Mammalian Embryos

Datar S, Bhonde RR
 
ABSTRACT: We have developed a simple shell-less chick embryo culture system to study glucose-induced malformations. This system involves the culturing of chick embryos from the second day to...

39. (Journal Article): Existence of Islet Regenerating Factors within the Pancreas

Kanitkar M, Bhonde R
 
ABSTRACT: Reduction in the functional mass of beta-cells is a common denominator in most forms of diabetes. Since the replicative potential of beta-cells is limited, the search for factors t...

40. (Journal Article): Approaches Towards Endogenous Pancreatic Regeneration

Banerjee M, Kanitkar M, Bhonde RR
 
ABSTRACT: The phenomenon of pancreatic regeneration in mammals has been well documented. It has been shown that pancreatic tissue is able to regenerate in several species of mammal after sur...