Site-Specific Intervention
Sub-Areas to Site-Specific Intervention:
T cells
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Treg cells
(0)
NK cells
(0)
B cells
(0)
AP cells
(0)
Costimulatory Molecules
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Combinatorial Treatment
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(Journal Article): {alpha}L integrin I domain cyclic peptide antagonist selectively inhibits T cell adhesion to pancreatic islet microvascular endothelium
Huang M, Matthews K, Siahaan TJ, Kevil CG
IN:
Am J Physiol Gastrointest Liver Physiol
2004; Epub(19)
Impact Factor(s) of Am J Physiol Gastrointest Liver Physiol: 3.479 (2004), 3.421 (2003), 3.66 (2001)
ABSTRACT:
Insulitis is a hallmark feature of autoimmune diabetes that ultimately results in islet beta cell destruction. We examined integrin requirements and specific inhibition of integrin...
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(Journal Article): Polyclonal Anti-T-Cell Therapy for Type 1 Diabetes Mellitus of Recent Onset
Saudek F, Havrdova T, Boucek P, Karasova L, Novota P, Skibova J
IN:
Rev Diabetic Stud
2004; 2(1):80-88
Impact Factor(s) of Rev Diabetic Stud: 0.125 (2006)
ABSTRACT:
The destruction of pancreatic beta-cells in type 1 diabetes mellitus is mediated by autoreactive T-lymphocyte clones. We initiated a prospective randomized controlled trial of poly...
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(Journal Article): Immunotherapy After Recent-Onset Type 1 Diabetes: Combinatorial Treatment for Achieving Long-Term Remission in Humans?
Bresson D, von Herrath M
IN:
Rev Diabetic Stud
2004; 1(3)
Impact Factor(s) of Rev Diabetic Stud: 0.125 (2006)
ABSTRACT:
Insulin-dependent diabetes mellitus (IDDM), or type 1 diabetes mellitus (TlDM), is one of the most common autoimmune diseases. This chronic disorder is thought to be caused by auto...
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