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Derived from Adult Islet Cells
Diabetes OD > Regeneration of Islets > Stem Cells > Other Cell Sources > Progenitors > Derived from Adult Islet Cells

Derived from Adult Islet Cells

(Journal Article): Nestin-positive progenitor cells derived from adult human pancreatic islets of Langerhans contain side population (SP) cells defined by expression of the ABCG2 (BCRP1) ATP-binding cassette transporter.
Lechner A, Leech CA, Abraham EJ, Nolan AL, Habener JF
IN: Biochem Biophys Res Commun 2002; 293(2):670-674
Impact Factor(s) of Biochem Biophys Res Commun: 2.904 (2004), 2.836 (2003), 2.935 (2002), 2.946 (2001)

ABSTRACT: The disease diabetes mellitus arises as a consequence of a failure of the beta-cells in the islets of Langerhans of the pancreas to produce insulin in the amounts required to meet ... Click HERE for details


(Journal Article): Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors.
Gu G, Dubauskaite J, Melton DA
IN: Development 2002; 129(10):2447- 2457
Impact Factor(s) of Development: 7.149 (2004), 7.663 (2003), 8.624 (2001)

ABSTRACT: The location and lineage of cells that give rise to endocrine islets during embryogenesis has not been established nor has the origin or identity of adult islet stem cells. We have... Click HERE for details


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