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(Journal Article): Nuclear and unclear functions of SUMO.
Seeler JS, Dejean A (Nuclear Organization and Oncogenesis Unit, INSERM U 579, Institut Pasteur, 28 rue du Dr. Roux, 75724 Paris Cedex 15, France.)
IN:
Nat Rev Mol Cell Biol
2003; 4(9):690-699
Impact Factor(s) of Nat Rev Mol Cell Biol: 29.852 (2005), 33.17 (2004), 35.041 (2003), 20.556 (2001)
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ABSTRACT: Post-translational modification by the ubiquitin-like SUMO protein is emerging as a defining feature of eukaryotic cells. Sumoylation has crucial roles in the regulatory challenges that face nucleate cells, including the control of nucleocytoplasmic signalling and transport and the faithful replication of a large and complex genome, as well as the regulation of gene expression.
TYPE OF PUBLICATION: Original article
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