(Journal Article): Association of class I major histocompatibility heavy and light chains induced by viral peptides.
 
Townsend A, Ohlen C, Bastin J, Ljunggren HG, Foster L, Karre K (Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford, UK.)
 
IN: Nature 1989; 340(6233):443-448
Impact Factor(s) of Nature: 29.273 (2005), 32.182 (2004), 30.979 (2003), 30.432 (2002), 27.955 (2001)

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ABSTRACT: We describe a cell in which association of a major histocompatibility complex class I heavy chain with beta 2-microglobulin is induced by a peptide derived from influenza nucleoprotein. Association of antigenic peptides with the binding site of class I molecules may be required for correct folding of the heavy chain, association with beta 2-microglobulin and transport of the antigen-MHC complex to the cell surface.

TYPE OF PUBLICATION: Original article

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