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Treg Cells
 
Diabetes OD > Diabetes Pathogenesis > T1DM > Autoimmunity > Defects in Self-Tolerance > Loss of Suppression Activity > Treg Cells

Treg Cells

Sub-Areas to Treg Cells:

TGF-beta-secretion (1)


(Journal Article): Defective suppressor function in CD4(+)CD25(+) T-cells from patients with type 1 diabetes.
 
Lindley S, Dayan CM, Bishop A, Roep BO, Peakman M, Tree TI
 
IN: Diabetes 2005; 54:92-99
Impact Factor(s) of Diabetes: 8.848 (2004), 8.298 (2003), 8.256 (2002), 7.7 (2001)

ABSTRACT: Type 1 diabetes is a T-cell-mediated disease that is associated with loss of immunological tolerance to self-antigens. The mechanisms involved in maintenance of peripheral toleranc... Click HERE for details

 

(Journal Article): Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis.
 
Viglietta V, Baecher-Allan C, Weiner HL, Hafler DA
 
IN: J Exp Med 2004; 199(7):971-979
Impact Factor(s) of J Exp Med: 14.588 (2004), 15.302 (2003), 15.34 (2001)

ABSTRACT: CD4+CD25+ regulatory T cells contribute to the maintenance of peripheral tolerance by active suppression because their deletion causes spontaneous autoimmune diseases in mice. Huma... Click HERE for details

 



 
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