11. (Journal Article): "Persistence of Diabetes" - Why Has Research into Type 1 Diabetes not Made Significant Advances?

Sia C, Weinem M
 
ABSTRACT: n/a

12. (Journal Article): Treatment of type 1 diabetes mellitus with DAB486-IL2, a toxin conjugate witch targets activated T-lymphocytes

Boitard C, Timsit J, Assan R, Mogenet A, Debussche X, Kaloustlan E, Attali JR, Chanson P, Chatenoud L, Woodworth T, et al.
 
ABSTRACT: Evidence point to autoreactive T-Iymphocytes in the pathogenesis of insulin-¬dependent diabetes mellitus (IDDM). Treatment with Cyclosporin A (7.5-10 mg/kg/d) of IDDM patients ind...

13. (Journal Article): Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers.

Almeida AR., Legrand N, Papiernik M, Freitas A
 
ABSTRACT: We show that the lymphoid hyperplasia observed in IL-2Ralpha- and IL-2-deficient mice is due to the lack of a population of regulatory cells essential for CD4 T cell homeostasis. I...

14. (Journal Article): IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells.

Vieira PL, Christensen JR, Minaee S, O'Neill EJ, Barrat FJ, Boonstra A, Barthlott T, Stockinger B, Wraith DC, O'Garra A
 
ABSTRACT: Regulatory T cells (T(Reg)) control immune responses to self and nonself Ags. The relationship between Ag-driven IL-10-secreting T(Reg) (IL-10-T(Reg)) and naturally occurring CD4(+...

15. (Journal Article): Proteins of the bcl-2 family in apoptosis signaling: from mechanistic insights to therapeutic opportunities.

Chan SL, Yu VC
 
ABSTRACT: 1. Proteins of the Bcl-2 family are central regulators of apoptosis and are thought to act primarily on the mitochondria. 2. Members of the Bcl-2 family possess either anti-apoptot...

16. (Journal Article): Glucose homeostasis in the nonobese diabetic mouse at the prediabetic stage.

Amrani A, Durant S, Throsby M, Coulaud J, Dardenne M, Homo-Delarche F
 
ABSTRACT: Because few data were available on glucose homeostasis at the early prediabetic stage in the nonobese diabetic (NOD) mouse, we investigated glycemia, insulinemia, and pancreatic in...

17. (Journal Article): Concordance for type 2 (non-insulin-dependent) diabetes mellitus in male twins

Newman B, Selby JV, King MC, Slemenda C, Fabsitz R, Friedman GD
 
ABSTRACT: Concordance for Type 2 (non-insulin-dependent) diabetes was determined in 250 monozygotic and 264 dizygotic white male twin pairs who participated in the National Heart, Lung, and ...

18. (Journal Article): The concept of space and competition in immune regulation.

Stockinger B, Barthlott T, Kassiotis G
 
ABSTRACT: Not availabe

19. (Journal Article): Glucagon-like peptide-1 (7-36 amide): a potent glucagonostatic and insulinotropic hormone.

Matsuyama T, Komatsu R, Namba M, Watanabe N, Itoh H, Tarui S
 
ABSTRACT: Glucagon-like peptide-1 (GLP-1) (1-37) and the fraction derived from it, GLP-1 (7-36 amide), are peptides encoded by the preproglucagon gene and possibly co-secreted with enteroglu...

20. (Journal Article): Glycated albumin induces superoxide generation in mesangial cells

Yoo C, Song C, Kim B, Hong H, Lee H
 
ABSTRACT: Background/Aims: Reactive oxygen species are involved in the pathogenesis of diabetic nephropathy. Amadori-modified glycated albumin modulates signaling pathways in mesangial cells...