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Your search for: 'Clinical*' Documents 71 - 80 of 175 matches
 

71. (Journal Article): Abnormal facilitative glucose transporter gene expression in human islet cell tumors.

Seino Y, Yamamoto T, Inoue K, Imamura M, Kadowaki S, Kojima H, Fujikawa J, Imura H
 
ABSTRACT: Our previous studies have shown that increased expression of GLUT1/erythrocyte and GLUT3/brain type glucose transporter genes in human tumors is associated with cellular transforma...

 

 

72. (Journal Article): Epithelial-to-mesenchymal transition generates proliferative human islet precursor cells.

Gershengorn MC, Hardikar AA, Wei C, Geras-Raaka E, Marcus-Samuels B, Raaka BM
 
ABSTRACT: Insulin-expressing beta cells, found in pancreatic islets, are capable of generating more beta cells even in the adult. We show that fibroblast-like cells derived from adult human ...

 

 

73. (Journal Article): Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets

Lumelsky N, Blondel O, Laeng P, Velasco I, Ravin R, McKay R
 
ABSTRACT: Although the source of embryonic stem (ES) cells presents ethical concerns, their use may lead to many clinical benefits if differentiated cell types can be derived from them and u...

 

 

74. (Journal Article): Encapsulated, genetically modified cells producing in vivo therapeutics.

Hauser O, Prieschl-Grassauer E, Salmons B
 
ABSTRACT: The ability to implant genetically modified cells in immuno-isolating materials has much potential for therapeutic use. This review presents the different types of polymer that can...

 

 

75. (Journal Article): Biologieal effects and metabolic rates of glucagon-like peptide-1 7-36 amide and glucagon-like peptide-1 7-37 in healthy subjects are indistinguishable.

0rskov C, Wettergren A, Holst JJ
 
ABSTRACT: The biological effects and the metabolism of the intestinal hormone glucagonlike peptide-1 7-36 amide and glucagonlike peptide-1 7-37 were studied in normal healthy subjects. GLP-1...

 

 

76. (Journal Article): All products of proglucagon are elevated in plasma from uremic patients.

0rskov C, Andreasen J, Holst JJ
 
ABSTRACT: We measured and characterized the proglucagon (PG) products in plasma obtained from nine uremic patients and six control subjects in the fasting state. The concentrations of PG pro...

 

 

77. (Journal Article): Proglucagon products in plasma of non-insulin dependent diabetics and nondiabetic controls in the fasting state and following oral glucose and intravenous arginine.

0rskov C, Jeppesen J, Madsbad S, Holst JJ
 
ABSTRACT: We investigated the major products of proglucagon (PG) processing in plasma in the fasting state, after intravenous arginine and after an oral glucose load in noninsulin-dependent ...

 

 

78. (Journal Article): The increase in risk of diabetes mellitus from exposure to second-generation antipsychotic agents

Citrome LL
 
ABSTRACT: This is a review of the evidence for a link between exposure to second-generation antipsychotic agents and the development of type 2 diabetes mellitus. Most of this evidence comes ...

 

 

79. (Journal Article): Role of hemochromatosis C282Y and H63D mutations in HFE gene in development of type 2 diabetes and diabetic nephropathy

Moczulski DK, Grzeszczak W, Gawlik B
 
ABSTRACT: OBJECTIVE: In patients with clinical hemochromatosis, the frequency of diabetes ranges from 20 to 50%, and the heterozygosity for the C282Y mutation in the HFE gene might be associ...

 

 

80. (Journal Article): New developments in the incretin concept.

Creutzfeldt W, Ebert R
 
ABSTRACT: Experimental and clinical work over the last 6 years has confirmed and broadened, but also challenged, the incretin concept. The nervous component of the entero-insular axis is sti...

 
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