41. (Journal Article): A Critical Appraisal of the Intrinsic Pancreatic Angiotensin-Generating System

Sernia C
 
ABSTRACT: The pancreas is a relative newcomer to the stable of tissues with an intrinsic angiotensin-generating system. The involvement of this system in pancreatic activity will be dependen...

42. (Journal Article): The Pancreatic Renin-Angiotensin System: Does It Play a Role in Endocrine Oncology?

Lam KY
 
ABSTRACT: The characterization of a local renin-angiotensin system in the pancreas has attracted much attention because of its potential clinical applications. A pancreatic renin-angiotensin...

43. (Journal Article): Local Renin-Angiotensin System in the Pancreas: The Significance of Changes by Chronic Hypoxia and Acute Pancreatitis

Leung PS
 
ABSTRACT: The circulating renin-angiotensin system (RAS) plays an important role in the maintenance of blood pressure and fluid homeostasis. Recently, there has been a shift of emphasis from...

44. (Journal Article): Pancreatic Head Mass: How Can We Treat It? Tumor: Surgical Treatment

Tihanyi TF, Pulay I, Winternitz T, Flautner L
 
ABSTRACT: Pancreatic carcinoma is a devastating disease. Untreated 5-year survival is 0%. The only possibility of being cured is given by surgical removal of the tumor. Pancreatoduodenectomy...

45. (Journal Article): Pancreatic Head Mass: What Can Be Done? Classification: The Clinical Point of View

Pulay I, Tihanyi TF, Flautner L
 
ABSTRACT: Surgeons frequently find pancreatic head mass when operating. The obvious difficulty is to make the correct preoperative differential diagnosis between chronic pancreatitis and pan...

46. (Journal Article): Clinical Usefulness of the Serum Carboxypeptidase B Activation Peptide in Acute Pancreatitis

Pezzilli R, Morselli-Labate AM, Barbieri AR, Platè L
 
ABSTRACT: OBJECTIVE: To assess the sensitivity and specificity of the serum carboxypeptidase B activation peptide in diagnosing and determining the severity of acute pancreatitis. PATIENTS: ...

47. (Journal Article): Synthetic exendin-4 (exenatide) significantly re-duces postprandial and fasting plasma glucose in subjects with type 2 diabetes.

Kolterman OG, Buse JB, Fineman MS, Gaines E, Heintz S, Bicsak TA, Taylor K, Kim D, Aisporna M, Wang Y, Baron AD
 
ABSTRACT: Despite the advent of new treatments, glucose control in the type 2 diabetes population is unsatisfactory. AC2993 (synthetic exendin-4; exenatide), a novel glucose-dependent insuli...

48. (Journal Article): Glucagon-like peptide 1 and its derivatives in the treatment of diabetes.

Nauck MA, Meier JJ
 
ABSTRACT: Glucagon-like peptide 1 (GLP-1) was discovered as an insulinotropic gut hormone, suggesting a physiological role as an incretin hormone, i.e., being responsible, in part, for the h...

49. (Journal Article): Interaction between GLP-1 and CCK-33 in inhibiting food intake and appetite in men.

Gutzwiller JP, Degen L, Matzinger D, Prestin S, Beglinger C
 
ABSTRACT: Glucagon-like peptide-1 (GLP-1) and CCK-33 were intravenously infused alone or in combination into normal weight men for 60 min before they were served a lunch of ham sandwiches, c...

50. (Journal Article): 1-[[(3-hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: a potent, selective, and orally bioavail-able dipeptidyl peptidase IV inhibitor with antihyperglycemic properties.

Villhauer EB, Brinkman JA, Naderi GB, Burkey BF, Dunning BE, Prasad K, Mangold BL, Russell ME, Hughes TE
 
ABSTRACT: Dipeptidyl peptidase IV (DPP-IV) inhibition has the potential to become a valuable therapy for type 2 diabetes. The synthesis and structure-activity relationship of a new DPP-IV in...