Inhibition of NF-kB activation
(Journal Article): Interleukin-11 inhibits NF-kappaB and AP-1 activation in islets and prevents diabetes induced with streptozotocin in mice.
Lgssiar A, Hassan M, Schott-Ohly P, Friesen N, Nicoletti F, Trepicchio WL, Gleichmann H
IN:
Exp Biol Med (Maywood)
2004; 229(5):425-436
Impact Factor(s) of Exp Biol Med (Maywood): 2.46 (2003)
ABSTRACT:
This laboratory has reported that multiple low doses of streptozotocin (MLD-STZ) similarly upregulate the T helper (Th)1-type proinflammatory cytokines tumor necrosis factor (TNF)-...
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(Journal Article): Dominant negative MyD88 proteins inhibit interleukin-1beta /interferon-gamma-mediated induction of nuclear factor kappa B-dependent nitrite production and apoptosis in beta cells.
Dupraz P, Cottet S, Hamburger F, Dolci W, Felley-Bosco E, Thorens B
IN:
J Biol Chem
2000; 275(48):37672–37678.-
Impact Factor(s) of J Biol Chem: 6.355 (2004), 6.482 (2003), 7.258 (2001)
ABSTRACT:
Insulin-dependent diabetes mellitus is an autoimmune disease in which pancreatic islet beta cells are destroyed by a combination of immunological and inflammatory mechanisms. In pa...
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(Journal Article): A20 inhibits cytokine-induced apoptosis and nuclear factor kappaB-dependent gene activation in islets.
Grey ST, Arvelo MB, Hasenkamp W, Bach FH, Ferran C
IN:
J Exp Med
1999; 190(8):1135–1146.-
Impact Factor(s) of J Exp Med: 14.588 (2004), 15.302 (2003), 15.34 (2001)
ABSTRACT:
Insulin-dependent diabetes mellitus (IDDM) is an autoimmune disease resulting from apoptotic destruction of beta cells in the islets of Langerhans. Low expression of antioxidants a...
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