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Calcium-Binding Proteins
 
Diabetes OD > Reversal/Prevention of Diabetes > T1DM > Beta-Cell Protection > Calcium-Binding Proteins

Calcium-Binding Proteins


(Journal Article): Expression of calbindin-D(28k) in a pancreatic islet beta-cell line protects against cytokine-induced apoptosis and necrosis.
 
Rabinovitch A, Suarez-Pinzon WL, Sooy K, Strynadka K, Christakos S
 
IN: Endocrinology 2001; 142(8):3649-3655
Impact Factor(s) of Endocrinology: 5.151 (2004), 5.063 (2003), 5.095 (2002), 4.971 (2001)

ABSTRACT: Cytokines produced by immune system cells that infiltrate pancreatic islets are candidate mediators of islet beta-cell destruction in autoimmune (type 1) diabetes mellitus. Because... Click HERE for details

 

(Journal Article): Vitamin D target proteins: function and regulation.
 
Christakos S, Barletta F, Huening M, Dhawan P, Liu Y, Porta A, Peng X
 
IN: J Cell Biochem 2003; 88(2):238-244
Impact Factor(s) of J Cell Biochem: 2.946 (2004), 2.664 (2003), 2.53 (2002), 2.536 (2001)

ABSTRACT: Recent findings have indicated that calbindin-D(28k), the first known target of vitamin D action, is present in osteoblasts and protects against TNF and glucocorticoid induced apop... Click HERE for details

 

(Journal Article): Calcium buffering properties of calbindin D28k and parvalbumin in rat sensory neurones.
 
Chard PS, Bleakman D, Christakos S, Fullmer CS, Miller RJ
 
IN: J Physiol 1993; 472:341-357
Impact Factor(s) of J Physiol: 4.346 (2004), 4.352 (2003), 4.476 (2001)

ABSTRACT: 1. We have examined the ability of the Ca(2+)-binding proteins (CABP) calbindin D28k and paravalbumin to modulate increases in the intracellular free Ca2+ concentration ([Ca2+]i), ... Click HERE for details

 



 
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