Sub-Areas to Other Cell Sources:
Umbilical Cord Blood
(1)
Replication
(0)
Acinar Cells
(5)
Progenitors
(12)
Endocrine Cells
(1)
Exocrine Cells
(0)
Transdifferentiation
(3)
(Journal Article): Cellular sources of new pancreatic beta cells and therapeutic implications for regenerative medicine.
Halban PA (Department of Genetic Medicine and Development, University Medical Centre, 1 rue Michel Servet, 1211 Geneva 4, Switzerland.,
philippe.halban@medecine.unige.ch
)
IN:
Nat Cell Biol
2004; 6(11):1021-1025
Impact Factor(s) of Nat Cell Biol: 20.649 (2004), 20.268 (2003), 18.285 (2002), 14.739 (2001)
ABSTRACT: Replacing missing insulin-producing beta cells to treat diabetes is a major challenge for regenerative medicine. A better understanding of beta-cell embryogenesis and regeneration in adult life is needed to devise means to derive these specialized cells in sufficiently large numbers from stem or precursor cells. It is also critical to ensure that any surrogate or regenerated beta cells have perfectly regulated insulin production, which is essential for physiological glucose homeostasis.
TYPE OF PUBLICATION: Review
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(Journal Article): Selective elimination of fibroblasts from cultures of normal human melanocytes.
Halaban R, Alfano FD
IN:
In Vitro
1984; 20(5):447-450
ABSTRACT: The main obstacle to establishing pure normal human melanocytes in vitro is contamination of the cultures by fibroblasts. The obstacle can be overcome by selective destruction of fibroblasts with geneticin ( G418 sulfate). Treatment of mixed cultures with this drug at a concentration of 100 micrograms/ml for two days results in pure cultures of normal human melanocytes.
TYPE OF PUBLICATION: Original article
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