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Degradation by Dipeptidyl Peptidase IV
 
Diabetes OD > Disease Management > T2DM > Metabolic Control > Anti-Hyperglycemic and Anti-Apoptotic Agents > Incretin Hormones > GLP-1 > Effectivity of GLP-1 in Therapy > Degradation by Dipeptidyl Peptidase IV

Degradation by Dipeptidyl Peptidase IV

Sub-Areas to Degradation by Dipeptidyl Peptidase IV:

Dipeptidyl-Peptidase IV Inhibitors (9)


(Journal Article): Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like pep-tide-1(7-36)amide, peptide histidine methionine and is respon-sible for their degradation in human serum.
 
Mentlein R, Gallwitz B, Schmidt WE
 
IN: Eur J Biochem 1993; 214(3):829-835

ABSTRACT: Peptides of the glucagon/vasoactive-intestinal-peptide (VIP) peptide family share a considerable sequence similarity at their N-terminus. They either start with Tyr-Ala, His-Ala or... Click HERE for details

 

(Journal Article): Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo.
 
Deacon CF, Johnsen AH, Holst JJ
 
IN: J Clin Endocrinol Metab 1995; 80(3):952-957

ABSTRACT: The metabolism of glucagon-like peptide-1 (GLP-1) has not been studied in detail, but it is known to be rapidly cleared from the circulation. Measurement by RIA is hampered by the ... Click HERE for details

 

(Journal Article): Rat intestinal brush border membrane dipeptidyl aminopeptidase IV: kinetic properties and substrate specificity of the purified enzyme.
 
Bella AM, Erikson RH, Kim YS
 
IN: Arch Biochem Biophys 1982; 218(1):156-162

ABSTRACT: n.a. Click HERE for details

 

(Journal Article): Are diprotin A (Ile-Pro-He) and diprotin B (Val-Pro-Leu) inhibitors or substrates for dipeptidyl peptidase IV?
 
Rahfeld J, Schierhorn M, Hartrodt B, Neubert K, Heins J
 
IN: Biochim Biophys Acta 1991; 1076:314-316

ABSTRACT: Dipeptidyl peptidase IV preferably hydrolyzes peptides and proteins with a penultimate proline residue. Umezawa and co-workers (Umezawa et al. (1984) J. Antibiotics 37, 422-425) re... Click HERE for details

 

(Journal Article): Dipeptidyl peptidase IV, a kidney brush border serine peptidase.
 
Kenny AJ, Booth AG, George SC, Ingram J, Kershaw D, Wood EJ, Young AR
 
IN: Biochem J 1976; 157:169-182

ABSTRACT: Dipeptidyl peptidase IV, an enzyme that releases dipeptides from substrates with N-terminal sequences of the forms X-Pro-Y or X-Ala-Y, was purified 300-fold from pig kidney cortex.... Click HERE for details

 

(Journal Article): Studies on dipeptidyl(amino)peptidase IV (glycylproline-naphthylamidase) in blood vessels.
 
Lojda Z
 
IN: Histochemistry 1979; 59:153-166

ABSTRACT: n.a. Click HERE for details

 

(Journal Article): Biogenesis of plasma membrane glycoproteins. Purification and properties of two rat liver plasma membrane glycoproteins.
 
Elovson J
 
IN: J Biol Chem 1980; 255:5807-5815
Impact Factor(s) of J Biol Chem: 6.355 (2004), 6.482 (2003), 7.258 (2001)

ABSTRACT: As a preliminary to a study of the biogenesis of individual plasma membrane glycoproteins, the marker enzyme nucleotide pyrophosphatase (NPPase) and a major rat liver plasma membra... Click HERE for details

 



 
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