Diabetes OD > Development and Function of Pancreas and Immunity > Immune System > Activation and Inhibition > Costimulation > B7	Display all items Journal Articles Discussion Articles Comments Discussions Conferences/Workshops Availabilities Grants/Funds Information/News

(Journal Article): The B7 family revisited.
 
Greenwald RJ, Freeman GJ, Sharpe AH
 
IN: Annu Rev Immunol 2005; 23(1):515-548
Impact Factor(s) of Annu Rev Immunol: 47.4 (2005), 52.431 (2004), 52.28 (2003), 54.455 (2002), 46.233 (2001)

ABSTRACT: The discovery of new functions for the original B7 family members, together with the identification of additional B7 and CD28 family members, have revealed new ways in which the B7... Click HERE for details

(Journal Article): B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells.
 
Tseng SY, Otsuji M, Gorski K, Huang X, Slansky JE, Pai SI, Shalabi A, Shin T, Pardoll DM, Tsuchiya H
 
IN: J Exp Med 2001; 193(7):839-846
Impact Factor(s) of J Exp Med: 14.588 (2004), 15.302 (2003), 15.34 (2001)

ABSTRACT: Dendritic cells (DCs), unique antigen-presenting cells (APCs) with potent T cell stimulatory capacity, direct the activation and differentiation of T cells by providing costimulato... Click HERE for details

(Journal Article): B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion.
 
Dong H, Zhu G, Tamada K, Chen L
 
IN: Nat Med 1999; 5(12):1365-1369
Impact Factor(s) of Nat Med: 28.878 (2005), 31.223 (2004), 30.55 (2003), 28.74 (2002), 27.906 (2001)

ABSTRACT: The B7 family members B7-1 and B7-2 interact with CD28 and constitute an essential T-cell co-stimulatory pathway in the initiation of antigen-specific humoral and cell-mediated imm... Click HERE for details

(Journal Article): Muscle fibres and cultured muscle cells express the B7.1/2-related inducible co-stimulatory molecule, ICOSL: implications for the pathogenesis of inflammatory myopathies.
 
Wiendl H, Mitsdoerffer M, Schneider D, Melms A, Lochmuller H, Hohlfeld R, Weller M
 
IN: Brain 2003; 126(Pt 5):1026-1035
Impact Factor(s) of Brain: 8.201 (2004), 7.967 (2003), 7.407 (2001)

ABSTRACT: Inducible co-stimulator ligand (ICOSL), a member of the B7 family of co-stimulatory molecules related to B7.1/2, regulates CD4 as well as CD8 T-cell responses via interaction with ... Click HERE for details

(Journal Article): B7 family molecules are favorably positioned at the human maternal-fetal interface.
 
Petroff MG, Chen L, Phillips TA, Azzola D, Sedlmayr P, Hunt JS
 
IN: Biol Reprod 2003; 68(5):1496-1504
Impact Factor(s) of Biol Reprod: 3.55 (2004), 3.646 (2003), 3.689 (2002), 3.508 (2001)

ABSTRACT: The human placenta utilizes both active and passive mechanisms to evade rejection by the maternal immune system. We investigated the pattern of expression of the B7 family of immun... Click HERE for details

(Journal Article): B7DC/PDL2 promotes tumor immunity by a PD-1-independent mechanism.
 
Liu X, Gao JX, Wen J, Yin L, Li O, Zuo T, Gajewski TF, Fu YX, Zheng P, Liu Y
 
IN: J Exp Med 2003; 197(12):1721-1730
Impact Factor(s) of J Exp Med: 14.588 (2004), 15.302 (2003), 15.34 (2001)

ABSTRACT: B7H1 (PDL1) and B7DC (PDL2) are two new members of the B7 family that can interact with PD-1, a putative negative regulator for immune function. Recent studies have provided eviden... Click HERE for details

(Journal Article): B7-H1 costimulation preferentially enhances CD28-independent T-helper cell function.
 
Tamura H, Dong H, Zhu G, Sica GL, Flies DB, Tamada K, Chen L
 
IN: Blood 2001; 97(6):1809-1816
Impact Factor(s) of Blood: 9.782 (2004), 10.12 (2003), 9.631 (2002), 9.273 (2001)

ABSTRACT: B7-H1 is a recently described B7-like molecule that costimulates T-cell growth and cytokine secretion without binding to CD28, cytotoxic T-lymphocyte antigen-4 (CTLA-4), and induci... Click HERE for details