Coronary Artery Disease


(Journal Article): The Association of Silent Coronary Artery Disease and Metabolic Syndrome in Chinese with Type 2 Diabetes Mellitus
 
Tsai JCR, Chang DM, Chung FM, Wu JC, Shin SJ, Lee YJ (Department of Clinical Research, Ping-Tung Christian Hospital, Ping-Tung 90000, Taiwan, t3275(at)ms25.hinet.net )
 
IN: Rev Diabetic Stud 2004; 1(1):18-28
Impact Factor(s) of Rev Diabetic Stud: 0.125 (2006)

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ABSTRACT: OBJECTIVES: Cardiovascular diseases account for approximately 75% of the deaths that occur in patients with diabetes. Because the clinical signs of coronary artery disease (CAD) in diabetic patients are hard to detect and routine screening is costly, it would be of great benefit to try to either prevent CAD from occurring or to detect it early and provide optimal care. Therefore, we analyzed the risk factors that might predict CAD in type 2 diabetes mellitus (T2DM) patients with no classical cardiac ischemic symptoms. METHODS: Using a resting 12-lead ECG, exercise tread-mill test, or thallium myocardial scintigraphy with exercise testing and dipyridamole injection, we screened diabetic patients already enrolled in a disease management program for possible CAD. We used diagnostic coronary angiography to confirm its presence. The definition and criteria of meta-bolic syndrome we used were modified from those outlined by the WHO classification and criteria of NCEP-ATP III. RESULTS: A total of 850 T2DM patients without clinical and electrocardiographic evidence of CAD were studied. Three hundred and sixty-eight asymptomatic patients with normal resting ECG were examined by exercise ECG test or thallium scintigraphy examination. Sixty patients considered to have a strong positive test or significant thallium myocardial ischemia received a diagnostic coronary angiography. Fifty-one were found to have significant coronary artery stenosis; 9 showed no significant ischemic lesion. While gender, patients’ age, known diabetes duration, serum uric acid level, smoking status, and the presence of WHO-metabolic syndrome defined hypertension and nephropathy were associated with silent CAD, logistic regression analysis found that the only predictor of silent CAD was the pres-ence of nephropathy. The components of NCEP-ATP III-metabolic syndrome were not found to be associated with silent CAD. CONCLUSIONS: A considerable proportion of T2DM patients have silent CAD. A diabetic patient with incipient or overt nephropathy should be examined for the presence of CAD. The definition of metabolic syndrome may be modified for early detection of CAD in patients with T2DM.

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(Journal Article): Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial.
 
Stamler J, Vaccaro O, Neaton JD, Wentworth D
 
IN: Diabetes Care 1993; 16:434-44
Impact Factor(s) of Diabetes Care: 7.071 (2004), 7.501 (2003), 5.477 (2002), 5.404 (2001)

TYPE OF PUBLICATION: Original article

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Hint: Your Response should directly apply to Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial.. Please check, if this context applies best to your contribution. Otherwise click HERE to change to the appropriate subject area. The actual subject area is Coronary Artery Disease.

 

(Journal Article): Increased incidence of coronary atherosclerosis in type 2 diabetes mellitus: mechanisms and management.
 
Hurst RT, Lee RW
 
IN: Ann Intern Med 2003; 139:824-83
Impact Factor(s) of Ann Intern Med: 13.114 (2004), 12.427 (2003), 11.416 (2002), 11.13 (2001)

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Hint: Your Response should directly apply to Increased incidence of coronary atherosclerosis in type 2 diabetes mellitus: mechanisms and management.. Please check, if this context applies best to your contribution. Otherwise click HERE to change to the appropriate subject area. The actual subject area is Coronary Artery Disease.

 

(Journal Article): Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction.
 
Haffner SM, Lehto S, Ronnemaa T, Pyorala K, Laakso M
 
IN: N Engl J Med 1998; 339:229-23
Impact Factor(s) of N Engl J Med: 44.016 (2005), 38.57 (2004), 34.833 (2003), 29.065 (2001)

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(Journal Article): Acute myocardial infarction in diabetes mellitus: lessons learned from ACE inhibition.
 
Nesto RW, Zarich S
 
IN: Circulation 1998; 97:12-1
Impact Factor(s) of Circulation: 12.563 (2004), 11.164 (2003), 10.255 (2002), 10.517 (2001)

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(Journal Article): Acute myocardial infarction in the diabetic patient: pathophysiology, clinical course and prognosis.
 
Jacoby RM, Nesto RW
 
IN: J Am Coll Cardiol 1992; 20:736-74
Impact Factor(s) of J Am Coll Cardiol: 9.133 (2004), 7.599 (2003), 6.278 (2002), 6.374 (2001)

TYPE OF PUBLICATION: Original article

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(Journal Article): Prevalence of asymptomatic myocardial ischaemia in diabetic subjects.
 
Koistinen MJ
 
IN: BMJ 1990; 301:92-9

TYPE OF PUBLICATION: Original article

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Hint: Your Response should directly apply to Prevalence of asymptomatic myocardial ischaemia in diabetic subjects.. Please check, if this context applies best to your contribution. Otherwise click HERE to change to the appropriate subject area. The actual subject area is Coronary Artery Disease.

 

(Journal Article): Prevalence of unrecognized silent myocardial ischaemia and its association with atherosclerotic risk factors in noninsulin-dependent diabetes mellitus.
 
MiSAD Group
 
IN: Am J Cardiol 1997; 79:134-13
Impact Factor(s) of Am J Cardiol: 3.14 (2004), 3.059 (2003), 2.637 (2001)

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(Journal Article): Consensus development conference on the diagnosis of coronary heart disease in people with diabetes.
 
American Diabetes Association
 
IN: Diabetes Care 1998; 21:1551-155
Impact Factor(s) of Diabetes Care: 7.071 (2004), 7.501 (2003), 5.477 (2002), 5.404 (2001)

TYPE OF PUBLICATION: Original article

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(Journal Article): ACC/AHA guidelines for exercise testing. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Exercise Testing)
 
Gibbons RJ, Balady GJ, Beasley JW, Bricker JT, Duvernoy WF, Froelicher VF, Mark DB, Marwick TH, McCallister BD, Thompson PD Jr, et al
 
IN: J Am Coll Cardiol 1997; 30:260-31
Impact Factor(s) of J Am Coll Cardiol: 9.133 (2004), 7.599 (2003), 6.278 (2002), 6.374 (2001)

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(Journal Article): Verona Diabetes Study. Diabetes duration and cause-specific mortality in the Verona Diabetes Study.
 
Brun E, Nelson RG, Bennett PH, Imperatore G, Zoppini G, Verlato G, Muggeo M
 
IN: Diabetes Care 2000; 23:1119-1123
Impact Factor(s) of Diabetes Care: 7.071 (2004), 7.501 (2003), 5.477 (2002), 5.404 (2001)

TYPE OF PUBLICATION: Original article

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(Journal Article): Prognosis for patients with different types of silent coronary artery disease.
 
Cohn PF
 
IN: Circulation 1987; 75(3 Pt 2):II33-3
Impact Factor(s) of Circulation: 12.563 (2004), 11.164 (2003), 10.255 (2002), 10.517 (2001)

TYPE OF PUBLICATION: Original article

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Hint: Your Response should directly apply to Prognosis for patients with different types of silent coronary artery disease.. Please check, if this context applies best to your contribution. Otherwise click HERE to change to the appropriate subject area. The actual subject area is Coronary Artery Disease.

 

(Journal Article): Significance of silent myocardial ischemia during exercise testing in patients with diabetes mellitus: A report from the Coronary Artery Surgery Study (CASS) Registry.
 
Weiner DA, Ryan TJ, Parsons L, Fisher LD, Chaitman BR, Sheffield LT, Tristani FE
 
IN: Am J Cardiol 1991; 68:729-73
Impact Factor(s) of Am J Cardiol: 3.14 (2004), 3.059 (2003), 2.637 (2001)

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Hint: Your Response should directly apply to Significance of silent myocardial ischemia during exercise testing in patients with diabetes mellitus: A report from the Coronary Artery Surgery Study (CASS) Registry.. Please check, if this context applies best to your contribution. Otherwise click HERE to change to the appropriate subject area. The actual subject area is Coronary Artery Disease.

 

(Journal Article): Exercise electrocardiogram and coronary heart disease mortality in the Multiple Risk Factor Intervention Trial.
 
Multiple Risk Factor Intervention Trial Research Group
 
IN: Am J Cardiol 1985; 55:16-2
Impact Factor(s) of Am J Cardiol: 3.14 (2004), 3.059 (2003), 2.637 (2001)

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Hint: Your Response should directly apply to Exercise electrocardiogram and coronary heart disease mortality in the Multiple Risk Factor Intervention Trial.. Please check, if this context applies best to your contribution. Otherwise click HERE to change to the appropriate subject area. The actual subject area is Coronary Artery Disease.

 

(Journal Article): Exercise-induced silent myocardial ischemia and coronary morbidity and mortality in middle-aged men.
 
Laukkanen JA, Kurl S, Lakka TA, Tuomainen TP, Rauramaa R, Salonen R, Eranen J, Salonen JT
 
IN: J Am Coll Cardiol 2001; 38:72-79
Impact Factor(s) of J Am Coll Cardiol: 9.133 (2004), 7.599 (2003), 6.278 (2002), 6.374 (2001)

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TYPE OF PUBLICATION: Original article

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Hint: Your Response should directly apply to Exercise-induced silent myocardial ischemia and coronary morbidity and mortality in middle-aged men.. Please check, if this context applies best to your contribution. Otherwise click HERE to change to the appropriate subject area. The actual subject area is Coronary Artery Disease.

 

(Journal Article): Hyperinsulinemia. A link between hypertension obesity and glucose intolerance.
 
Modan M, Halkin H, Almog S, Lusky A, Eshkol A, Shefi M, Shitrit A, Fuchs Z
 
IN: J Clin Invest 1985; 75:809-817
Impact Factor(s) of J Clin Invest: 14.204 (2004), 14.307 (2003), 14.118 (2001)

ABSTRACT: not available.

TYPE OF PUBLICATION: Original article

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Hint: Your Response should directly apply to Hyperinsulinemia. A link between hypertension obesity and glucose intolerance.. Please check, if this context applies best to your contribution. Otherwise click HERE to change to the appropriate subject area. The actual subject area is Coronary Artery Disease.

 

(Journal Article): Cardiovascular morbidity and mortality associated with the metabolic syndrome.
 
Isomaa B, Almgren P, Tuomi T, Forsen B, Lahti K, Nissen M, Taskinen MR, Groop L
 
IN: Diabetes Care 2001; 24:683-68
Impact Factor(s) of Diabetes Care: 7.071 (2004), 7.501 (2003), 5.477 (2002), 5.404 (2001)

TYPE OF PUBLICATION: Original article

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Respond on this Journal Article!
Hint: Your Response should directly apply to Cardiovascular morbidity and mortality associated with the metabolic syndrome.. Please check, if this context applies best to your contribution. Otherwise click HERE to change to the appropriate subject area. The actual subject area is Coronary Artery Disease.

 

(Journal Article): The metabolic syndrome is associated with advanced vascular damage in patients with coronary heart disease, stroke, peripheral arterial disease or abdominal aortic aneurysm.
 
Olijhoek JK, Van Der Graaf Y, Banga JD, Algra A, Rabelink TJ, Visseren FL for the SMART Study Group
 
IN: Eur Heart J 2004; 25:342-34
Impact Factor(s) of Eur Heart J: 6.247 (2004), 5.997 (2003), 6.131 (2002), 5.153 (2001)

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Hint: Your Response should directly apply to The metabolic syndrome is associated with advanced vascular damage in patients with coronary heart disease, stroke, peripheral arterial disease or abdominal aortic aneurysm.. Please check, if this context applies best to your contribution. Otherwise click HERE to change to the appropriate subject area. The actual subject area is Coronary Artery Disease.

 

(Journal Article): Definition, diagnosis and classification of diabetes mellitus and its complications.
 
Alberti KG, Zimmet PZ
 
IN: Diabet Med 1998; 15:539-55
Impact Factor(s) of Diabet Med: 2.621 (2004), 2.235 (2003), 2.678 (2001)

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Hint: Your Response should directly apply to Definition, diagnosis and classification of diabetes mellitus and its complications.. Please check, if this context applies best to your contribution. Otherwise click HERE to change to the appropriate subject area. The actual subject area is Coronary Artery Disease.

 

(Journal Article): Executive summary of the third report of The National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III).
 
Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults
 
IN: JAMA 2001; 285:2486-2497
Impact Factor(s) of JAMA: 23.332 (2005), 24.831 (2004), 21.455 (2003), 17.569 (2001)

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Hint: Your Response should directly apply to Executive summary of the third report of The National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III).. Please check, if this context applies best to your contribution. Otherwise click HERE to change to the appropriate subject area. The actual subject area is Coronary Artery Disease.

 

(Journal Article): ACE gene insertion/deletion polymorphism associated with 1998 World Health Organization definition of metabolic syndrome in Chinese type 2 diabetic patients.
 
Lee YJ, Tsai JC
 
IN: Diabetes Care 2002; 25:1002-1008
Impact Factor(s) of Diabetes Care: 7.071 (2004), 7.501 (2003), 5.477 (2002), 5.404 (2001)

TYPE OF PUBLICATION: Original article

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Respond on this Journal Article!
Hint: Your Response should directly apply to ACE gene insertion/deletion polymorphism associated with 1998 World Health Organization definition of metabolic syndrome in Chinese type 2 diabetic patients.. Please check, if this context applies best to your contribution. Otherwise click HERE to change to the appropriate subject area. The actual subject area is Coronary Artery Disease.

 

(Journal Article): Association of a 27-bp repeat polymorphism in intron 4 of endothelial constitutive nitric oxide synthase gene with serum uric acid levels in Chinese subjects with type 2 diabetes.
 
Lee YJ, Chang DM, Tsai JC
 
IN: Metabolism 2003; 52:1448-1453
Impact Factor(s) of Metabolism: 2.143 (2004), 2.013 (2003), 1.931 (2001)

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Hint: Your Response should directly apply to Association of a 27-bp repeat polymorphism in intron 4 of endothelial constitutive nitric oxide synthase gene with serum uric acid levels in Chinese subjects with type 2 diabetes.. Please check, if this context applies best to your contribution. Otherwise click HERE to change to the appropriate subject area. The actual subject area is Coronary Artery Disease.

 

(Journal Article): Association of resistin gene 3'-untranslated region +62G-->A polymorphism with type 2 diabetes and hypertension in a Chinese population.
 
Tan MS, Chang SY, Chang DM, Tsai JC, Lee YJ
 
IN: J Clin Endocrinol Metab 2003; 88:1258-1263
Impact Factor(s) of J Clin Endocrinol Metab: 5.778 (2004), 5.873 (2003), 5.16 (2001)

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ABSTRACT: Resistin, a recently discovered polypeptide, antagonizes insulin action and may play a part in the pathogenesis of insulin resistance. This study investigates whether resistin gene polymorphism can be associated with type 2 diabetes. We studied 1102 Chinese type 2 diabetes patients and 743 subjects without diabetes. The resistin 3'-untranslated region (UTR) +62G->A polymorphism was determined by PCR. Type 2 diabetes subjects had a lower frequency of resistin gene 3'UTR +62A allele (GG:GA/AA, 83.5%:16.5%) than the controls (GG:GA/AA, 75.1%:24.9%; odds ratio, 1.524; 95% confidence interval, 1.268-1.831; P < 0.001). Unexpectedly, diabetic patients with the GG genotype had a higher prevalence of hypertension (GG:GA/AA, 49.8%:36.2%; odds ratio, 1.375; 95% confidence interval, 1.116-1.693; P = 0.001). Logistic regression analysis confirmed that the resistin gene 3'UTR +62G->A polymorphism acts as an independent contributing factor to type 2 diabetes and hypertension. The mean systolic and diastolic blood pressure levels in diabetic subjects with the GG genotype (144 ± 21/87 ± 13 mm Hg) were significantly higher than those in subjects with GA/AA variants (139 ± 21/84 ± 14 mm Hg; P = 0.004 and P = 0.002, respectively). Multiple linear regression analysis showed resistin gene polymorphism to be an independent factor associated with systolic and diastolic blood pressures in type 2 diabetes patients. These findings suggest that resistin may play a role in the pathogenesis of type 2 diabetes and insulin resistance-related hypertension.

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ABSTRACT: n/a

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(Journal Article): Cohort study of predictive value of urinary albumin excretion for atherosclerotic vascular disease in patients with insulin dependent diabetes.
 
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(Journal Article): The stages in diabetic renal disease. With emphasis on the stage of incipient diabetic nephropathy.
 
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ABSTRACT: not available.

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(Journal Article): Microalbuminuria as predictor of vascular disease in non-diabetic subjects.
 
Yudkin JS, Forrest RD, Jackson CA
 
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(Journal Article): Microalbuminuria predicts cardiovascular events and renal insufficiency in patients with essential hypertension.
 
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(Journal Article): Arterial hypertension, microalbuminuria, and risk of ischemic heart disease.
 
Jensen JS, Feldt-Rasmussen B, Strandgaard S, Schroll M, Borch-Johnsen K
 
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(Journal Article): Renal and systemic transvascular albumin leakage in severe atherosclerosis.
 
Jensen JS
 
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(Journal Article): Albuminuria reflects widespread vascular damage.
 
Deckert T, Feldt-Rasmussen B, Borch-Johnsen K, Jensen T, Kofoed-Enevoldsen A
 
IN: Diabetologia 1989; 32:219-226
Impact Factor(s) of Diabetologia: 5.583 (2004), 5.689 (2003), 5.136 (2002), 6.299 (2001)

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ABSTRACT: not available.

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(Journal Article): Predictive value of cardiac autonomic neuropathy in diabetic patients with or without silent myocardial ischemia.
 
Valensi P, Sachs RN, Harfouche B, Lormeau B, Paries J, Cosson E, Paycha F, Leutenegger M, Attali JR
 
IN: Diabetes Care 2001; 24:339-343
Impact Factor(s) of Diabetes Care: 7.071 (2004), 7.501 (2003), 5.477 (2002), 5.404 (2001)

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(Journal Article): Silent coronary artery disease in diabetes—a feature of autonomic neuropathy or accelerated atherosclerosis? Diabetologia 2001.
 
Airaksinen KE
 
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Impact Factor(s) of Diabetologia: 5.583 (2004), 5.689 (2003), 5.136 (2002), 6.299 (2001)

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(Journal Article): Association between silent coronary artery disease, diabetes, and autonomic neuropathy. Fact of fallacy?
 
Airaksinen KE, Koistinen MJ
 
IN: Diabetes Care 1992; 15:288-292
Impact Factor(s) of Diabetes Care: 7.071 (2004), 7.501 (2003), 5.477 (2002), 5.404 (2001)

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