1. (Journal Article): Novel Insights in the Regulation of the Immune System: A Report on the FASEB Summer Research Conference on Autoimmunity, 2003

Gronski MA
 
ABSTRACT: The bi-annual FASEB autoimmunity conference organized last year by Betty Diamond and Stephen Miller brought together some 150 delegates studying various aspects of autoimmune disea...

2. (Journal Article): Formation of insulin positive cells in implants of human pancreatic duct cell preparations from young donors.

Bogdani M, Lefebvre B, Buelens N, Bock T, Pipeleers-Marichal M, Int Veld P, Pipeleers D
 
ABSTRACT: AIMS/HYPOTHESIS: Pancreatic ducts are considered as potential sites for neogenesis of beta cells. In vitro studies have reported formation of islets from postnatal human and rodent...

3. (Journal Article): C-peptide enhances insulin-mediated cell growth and protection against high glucose induced apoptosis in SH-SY5Y cells.

Li Z-G, Zhang W, Sima AAF
 
ABSTRACT: BACKGROUND: We have previously reported that C-peptide exerts preventive and therapeutic effects on diabetic neuropathy in type 1 diabetic BB/Wor-rats and that it prevents duration...

4. (Journal Article): Formation of insulin-positive cells in implants of human pancreatic duct cell preparations from young donors.

Bogdani M, Lefebvre V, Buelens N, Bock T, Pipeleers-Marichal M, In't Veld P, Pipeleers D
 
ABSTRACT: AIMS/HYPOTHESIS: Pancreatic ducts are considered as potential sites for neogenesis of beta cells. In vitro studies have reported formation of islets from postnatal human and rodent...

5. (Journal Article): Increased Transcriptional Preproinsulin II Beta-Cell Activity in Neonatal Nonobese Diabetic Mice: In Situ Hybridization Analysis

Throsby M, Coulaud J, Durant S, Homo-Delarche F
 
ABSTRACT: In the prediabetic nonobese diabetic (NOD) mouse, a spontaneous model of type 1 diabetes, we previously reported transient postweaning hyperinsulinemia followed by progressive isle...

6. (Journal Article): Glucagon-like peptide I analogues: effects on insulin secretion and adenosine 3',5'-monophosphate formation.

Gefel D, Hendrick GK, Mojsov S, Habener J, Weir GE
 
ABSTRACT: Glucagon-like peptide 1-(7-37) [GLP-I-(7-37)] is a 31-amino acid hormone which may have an important role in the regulation of insulin secretion, It is processed from preproglucago...

7. (Journal Article): SOCS-1 protein prevents Janus Kinase/STAT-dependent inhibition of beta cell insulin gene transcription and secretion in response to interferon-gamma.

Cottet S, Dupraz P, Hamburger F, Dolci W, Jaquet M, Thorens B
 
ABSTRACT: In the pathogenesis of type I diabetes mellitus, activated leukocytes infiltrate pancreatic islets and induce beta cell dysfunction and destruction. Interferon (IFN)-gamma, tumor n...

8. (Journal Article): Portal venous pressure changes after sequential clinical islet transplantation.

Casey JJ, Lakey JR, Ryan EA, Paty BW, Owen R, O'Kelly K, Nanji S, Rajotte RV, Korbutt GS, Bigam D, Kneteman NN, Shapiro AM
 
ABSTRACT: BACKGROUND: Sequential pancreatic islet transplantation via the portal vein has led to insulin independence in patients with type 1 diabetes. Complications associated with the inje...

9. (Journal Article): Delivery of Bcl-XL or its BH4 domain by protein transduction inhibits apoptosis in human islets.

Klein D, Ribeiro MM, Mendoza V, Jayaraman S, Kenyon NS, Pileggi A, Molano RD, Inverardi L, Ricordi C, Pastori RL
 
ABSTRACT: Viability of isolated islets is one of the main obstacles limiting islet transplantation success. It has been reported that overexpression of Bcl-2/Bcl-XL proteins enhances islet v...

10. (Journal Article): Significance of silent myocardial ischemia during exercise testing in patients with diabetes mellitus: A report from the Coronary Artery Surgery Study (CASS) Registry.

Weiner DA, Ryan TJ, Parsons L, Fisher LD, Chaitman BR, Sheffield LT, Tristani FE