1. (Journal Article): Glycated albumin induces superoxide generation in mesangial cells

Yoo C, Song C, Kim B, Hong H, Lee H
 
ABSTRACT: Background/Aims: Reactive oxygen species are involved in the pathogenesis of diabetic nephropathy. Amadori-modified glycated albumin modulates signaling pathways in mesangial cells...

2. (Journal Article): Long-term postoperative mortality in diabetic patients undergoing major non-cardiac surgery

Juul AB, Wetterslev J, Kofoed-Enevoldsen A
 
ABSTRACT: BACKGROUND AND OBJECTIVE: The prognosis of diabetic patients after surgery remains controversial. Some suggest that the rates of death and complications today are almost identical ...

3. (Journal Article): Glucagon-like peptide-1 (7-36 amide): a potent glucagonostatic and insulinotropic hormone.

Matsuyama T, Komatsu R, Namba M, Watanabe N, Itoh H, Tarui S
 
ABSTRACT: Glucagon-like peptide-1 (GLP-1) (1-37) and the fraction derived from it, GLP-1 (7-36 amide), are peptides encoded by the preproglucagon gene and possibly co-secreted with enteroglu...

4. (Journal Article): Existence of Islet Regenerating Factors within the Pancreas

Kanitkar M, Bhonde R
 
ABSTRACT: Reduction in the functional mass of beta-cells is a common denominator in most forms of diabetes. Since the replicative potential of beta-cells is limited, the search for factors t...

5. (Journal Article): Reversal of lesions of diabetic nephropathy after pancreas transplantation.

Fioretto P, Steffes MW, Sutherland DE, Goetz FC, Mauer M
 
ABSTRACT: BACKGROUND: In patients with type I diabetes mellitus who do not have uremia and have not received a kidney transplant, pancreas transplantation does not ameliorate established les...

6. (Journal Article): "Persistence of Diabetes" - Why Has Research into Type 1 Diabetes not Made Significant Advances?

Sia C, Weinem M
 
ABSTRACT: n/a

7. (Journal Article): Genetics of diabetic nephropathy in the Pima Indians

Imperatore G, Knowler WC, Nelson RG, Hanson RL
 
ABSTRACT: Diabetic nephropathy is the leading cause of renal failure in industrialized countries. There is strong evidence that diabetic nephropathy is influenced by genetic factors. Studies...

8. (Journal Article): Treatment of type 1 diabetes mellitus with DAB486-IL2, a toxin conjugate witch targets activated T-lymphocytes

Boitard C, Timsit J, Assan R, Mogenet A, Debussche X, Kaloustlan E, Attali JR, Chanson P, Chatenoud L, Woodworth T, et al.
 
ABSTRACT: Evidence point to autoreactive T-Iymphocytes in the pathogenesis of insulin-¬dependent diabetes mellitus (IDDM). Treatment with Cyclosporin A (7.5-10 mg/kg/d) of IDDM patients ind...

9. (Journal Article): Approaches Towards Endogenous Pancreatic Regeneration

Banerjee M, Kanitkar M, Bhonde RR
 
ABSTRACT: The phenomenon of pancreatic regeneration in mammals has been well documented. It has been shown that pancreatic tissue is able to regenerate in several species of mammal after sur...

10. (Journal Article): Islet Generation from Intra Islet Precursor Cells of Diabetic Pancreas: In Vitro Studies Depicting In Vivo Differentiation

Banerjee M, Bhonde RR
 
ABSTRACT: CONTEXT: Beta-cells have a limited replicative capacity; hence, there is always a quest for sources of islet regeneration to compensate for the loss of functional beta-cells in dia...