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Your search for: 'Macfarlane* AND Frayling* AND Ellard* AND Evans* AND Allen* AND Bulman* AND Ayres* AND Shepherd* AND Clark* AND Millward* AND Missense* AND mutations* AND insulin* AND promoter* AND gene* AND predispose* AND type* AND diabetes*'

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1. (Journal Article): Missense mutations in the insulin promoter factor-1 gene predispose to type 2 diabetes

Macfarlane WM, Frayling TM, Ellard S, Evans JC, Allen LI, Bulman MP, Ayres S, Shepherd M, Clark P, Millward A, Demaine A, Wilkin T, Docherty K, Hattersley AT

ABSTRACT: The transcription factor insulin promoter factor-1 (IPF-1) plays a central role in both the development of the pancreas and the regulation of insulin gene expression in the mature ...

» Diabetes OD » Diabetes Pathogenesi... » T2DM » Genetics » Mutations » IPF-1 Gene » Journal Article
submitted: Dec 19, 2004

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