1. (Journal Article): A20 inhibits cytokine-induced apoptosis and nuclear factor kappaB-dependent gene activation in islets.
Grey ST, Arvelo MB, Hasenkamp W, Bach FH, Ferran C
ABSTRACT:
Insulin-dependent diabetes mellitus (IDDM) is an autoimmune disease resulting from apoptotic destruction of beta cells in the islets of Langerhans. Low expression of antioxidants a...
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2. (Journal Article): The NF-kappaB pathway as a potential target for autoimmune disease therapy.
Bacher S, Schmitz ML
ABSTRACT:
A battery of proinflammatory agents triggers the activation of NF-kappaB. This inducible transcription factor participates in the expression of an exceptionally large number of tar...
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3. (Journal Article): Insulin-dependent diabetes mellitus as an autoimmune disease.
Bach JF
ABSTRACT:
IDDM is unquestionably an autoimmune disease, as reflected by the presence of beta-cell-reactive autoantibodies and T cells, T cell-mediated transfer of the disease in nondiabetic ...
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