1. (Journal Article): Pancreatic Stone Protein of Pancreatic Calculi in Chronic Calcified Pancreatitis in Man

Jin CX, Naruse S, Kitagawa M, Ishiguro H, Kondo T, Hayakawa S, Hayakawa T
 
ABSTRACT: CONTEXT: The role of protein components of pancreatic secretions has been controversial in pancreatic stone formation. OBJECTIVE: To study the lithogenic role of pancreatic stone p...

2. (Journal Article): Subcutaneously Inoculated Cells and Implanted Pancreatic Cancer Tissue Show Different Patterns of Metastases in Syrian Golden Hamsters

Morioka CY, Saito S, Ohzawa K, Asano S , Hibino Y, Nakada Y, Kita KI, Watanabe A
 
ABSTRACT: CONTEXT: We studied behavior of the subcutaneously implanted pancreatic tumors and the process of metastasis using syngeneic Syrian golden hamsters. DESIGN: HaP-T1, a cell line der...

3. (Journal Article): Effect on glycemic control of exenatide (synthetic exendin-4) additive to existing metformin and/or sulfonylurea treatment in patients with type 2 diabetes.

Fineman MS, Bicsak TA, Shen LZ, Taylor K, Gaines E, Varns A, Kim D, Baron AD
 
ABSTRACT: OBJECTIVE: AC2993 (synthetic exendin-4; exenatide) is a peptide that enhances glucose-dependent insulin secretion, suppresses inappropriately elevated glucagon secretion, and slows...

4. (Journal Article): Pharmacokinetics, pharmacodynamics, and safety of exenatide in patients with type 2 diabetes mellitus.

Kolterman OG, Kim DD, Shen L, Ruggles JA, Nielsen LL, Fineman MS, Baron AD
 
ABSTRACT: PURPOSE: The pharmacology and tolerability of exenatide in patients with type 2 diabetes mellitus were studied. METHODS: Two randomized, single-blind, placebo-controlled studies we...

5. (Journal Article): Synthetic exendin-4 (exenatide) significantly re-duces postprandial and fasting plasma glucose in subjects with type 2 diabetes.

Kolterman OG, Buse JB, Fineman MS, Gaines E, Heintz S, Bicsak TA, Taylor K, Kim D, Aisporna M, Wang Y, Baron AD
 
ABSTRACT: Despite the advent of new treatments, glucose control in the type 2 diabetes population is unsatisfactory. AC2993 (synthetic exendin-4; exenatide), a novel glucose-dependent insuli...

6. (Journal Article): Glucagon-like peptide-1, a gastrointestinal hormone with a pharmaceutical potential.

Holst JJ
 
ABSTRACT: Glucagon-like peptide-1 (GLP-1) is an insulinotropic hormone secreted from endocrine cells in the gut mucosa in response to meal ingestion. It is an important incretin hormone; mic...

7. (Journal Article): Molecular cloning and characterization of the human voltage-gated calcium channel alpha(2)delta-4 subunit.

Qin N, Yagel S, Momplaisir ML, Codd EE, D'Andrea MR
 
ABSTRACT: The voltage-gated calcium channel is composed of a pore-forming alpha(1) subunit and several regulatory subunits: alpha(2)delta, beta, and gamma. We report here the identification ...

8. (Journal Article): Incretin mimetics as emerging treatments for type 2 diabetes.

Joy SV, Rodgers PT, Scates AC
 
ABSTRACT: OBJECTIVE: To review the physiology, pharmacology, and clinical efficacy of glucagon-like peptide (GLP-1) and the incretin mimetics exenatide and liraglutide in clinical studies. D...

9. (Journal Article): Antidiabetic, antioxidant and antihyperlipidemic status of heliotropium zeylanicum extract on streptozotocin-induced diabetes in rats

Murugesh K, Yeligar V, Dash DK, Sengupta P, Maiti BC, Maity TK.
 
ABSTRACT: The potential role of the methanolic extract of Heliotropium zeylanicum (BURM.F) LAMK (MEHZ) in the treatment of diabetes along with its antioxidant and antihyperlipidemic effects ...