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Your search for: 'An* AND Nature*' |
Documents 1 - 10 of 73 matches |
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1. (Journal Article): Making sense of glucose sensing.
Efrat S ABSTRACT:
n.a.
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Diabetes OD
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Regeneration of Isle...
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Stem Cells
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Embryonic Stem Cells
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Journal Article
submitted: Jun 13, 2006 |
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2. (Journal Article): Assessing the validity of the association be-tween the SUMO4 M55V variant and risk of type 1 diabetes.
Smyth DJ, Howson JM, Lowe CE, Walker NM, Lam AC, Nutland S, Hutchings J, Tuomilehto-Wolf E, Tuomilehto J, Guja C, Ionescu-Tirgoviste C, Undlien DE, Ronningen KS, Savage D, Dunger DB, Twells RC, McArdle WL, Strachan DP, Todd JA. ABSTRACT:
Not available.
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Diabetes OD
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Diabetes Pathogenesi...
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T1DM
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Autoimmunity
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Genetics of Autoimmu...
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SUMO4
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Polymorphism
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Journal Article
submitted: Aug 24, 2005 |
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3. (Journal Article): Biochemistry and molecular cell biology of diabetic complications.
Brownlee M |
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Diabetes OD
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Diabetic Complicatio...
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Neural
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Journal Article
submitted: Apr 28, 2005 |
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4. (Journal Article): Beginning at the end with SUMO.
Matunis MJ, Pickart CM ABSTRACT:
The crystal structure of a four-protein complex comprising a SUMO ligase (E3), a SUMOylated protein substrate, and the cognate SUMO-conjugating enzyme sheds new light on catalysis,...
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Diabetes OD
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Diabetes Pathogenesi...
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T1DM
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Autoimmunity
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Genetics of Autoimmu...
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SUMO4
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Journal Article
submitted: Aug 24, 2005 |
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5. (Journal Article): Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus
Horikawa Y, Oda N, Cox NJ, Li X, Orho-Melander M, Hara M, Hinokio Y, Lindner TH, Mashima H, Schwarz PE, del Bosque-Plata L, Horikawa Y, Oda Y, Yoshiuchi I, Colilla S, Polonsky KS, Wei S, Concannon P, Iwasaki N, Schulze J, Baier LJ, Bogardus C, Groop L, Boerwinkle E, Hanis CL, Bell GI ABSTRACT:
Type 2 or non-insulin-dependent diabetes mellitus (NIDDM) is the most common form of diabetes worldwide, affecting approximately 4% of the world's adult population. It is multifact...
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Diabetes OD
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Diabetes Pathogenesi...
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T2DM
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Genetics
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Susceptibility Genes
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NIDDM1
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Calpain-10 Gene
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Journal Article
submitted: Dec 19, 2004 |
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6. (Journal Article): Bone marrow-derived stem cells initiate pancreatic regeneration.
Hess D, Li L, Martin M, Sakano S, Hill D, Strutt B, Thyssen S, Gray DA, Bhatia M ABSTRACT:
We show that transplantation of adult bone marrow-derived cells expressing c-kit reduces hyperglycemia in mice with streptozotocin-induced pancreatic damage. Although quantitative ...
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Diabetes OD
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Regeneration of Isle...
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Stem Cells
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Other Cell Sources
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Progenitors
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Journal Article
submitted: May 19, 2005 |
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7. (Journal Article): Characterization of a nuclear-factor-kappa B (NFkappaB) genetic marker in type 1 diabetes (T1DM) families.
Gylvin T, Bergholdt R, Nerup J, Pociot F ABSTRACT:
Cytokine-induced beta-cell death is an important factor in the pathogenesis of type 1 diabetes mellitus (T1DM). The transcription factor NFkappaB plays an important role in cytokin...
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Diabetes OD
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Diabetes Pathogenesi...
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T1DM
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Autoimmunity
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Genetics of Autoimmu...
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Immune Response Medi...
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NF-κB
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Journal Article
submitted: Aug 24, 2005 |
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8. (Journal Article): NFkappaB polymorphisms and susceptibility to type 1 diabetes.
Hegazy DM, O'Reilly DA, Yang BM, Hodgkinson AD, Millward BA, Demaine AG ABSTRACT:
Nuclear factor kappa B (NFkappaB) is an important transcription factor that is involved in the response to oxidative stress and inflammation. Recent studies suggest that it may be ...
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Diabetes OD
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Diabetes Pathogenesi...
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T1DM
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Autoimmunity
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Genetics of Autoimmu...
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Immune Response Medi...
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NF-κB
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Polymorphism
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Journal Article
submitted: Aug 24, 2005 |
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9. (Journal Article): SUMO: a regulator of gene expression and genome integrity.
Muller S, Ledl A, Schmidt D ABSTRACT:
Post-translational modification with the ubiquitin-like SUMO protein is involved in the regulation of many cellular key processes. The SUMO system modulates signal transduction pat...
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Diabetes OD
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Diabetes Pathogenesi...
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T1DM
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Autoimmunity
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Genetics of Autoimmu...
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SUMO4
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Journal Article
submitted: Aug 24, 2005 |
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10. (Journal Article): Functional variants in SUMO4, TAB2, and NFkappaB and the risk of type 1 diabetes.
Kosoy R, Concannon P ABSTRACT:
Several functional genetic variants that can potentially modulate the activity of NFkappaB have been recently described. As reduced NFkappaB activity has been implicated in risk fo...
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Diabetes OD
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Diabetes Pathogenesi...
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T1DM
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Autoimmunity
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Genetics of Autoimmu...
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SUMO4
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Polymorphism
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Journal Article
submitted: Aug 24, 2005 |
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