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Your search for: 'Use*' Documents 121 - 130 of 255 matches
 

121. (Journal Article): Insulin gene transfer enhances the function of human islet grafts.

Deng S, Vatamaniuk M, Lian MM, Doliba N, Wang J, Bell E, Wolf B, Raper S, Matschinsky FM, Markmann JF
 
ABSTRACT: AIMS/HYPOTHESIS: Recent success in islet transplantation renews the hope for the complete cure of patients afflicted with Type 1 diabetes. However, in the Edmonton series, two to f...

 

 

122. (Journal Article): Preservation of human islet cell functional mass by anti-oxidative action of a novel SOD mimic compound.

Bottino R, Balamurugan AN, Bertera S, Pietropaolo M, Trucco M, Piganelli JD
 
ABSTRACT: The most commonly used technical approach to isolate human pancreatic islets intended for allotransplants generates a product that is hampered by mechanical and chemical insults, w...

 

 

123. (Journal Article): Adenoviral gene transfer of erythropoietin confers cytoprotection to isolated pancreatic islets.

Fenjves ES, Ochoa MS, Gay-Rabinstein C, Molano RD, Pileggi A, Mendez AJ, Inverardi L, Ricordi C
 
ABSTRACT: BACKGROUND: The transfer of cytoprotective genes to isolated pancreatic islets may contribute to their enhanced survival in the transplant setting. Our laboratory established the e...

 

 

124. (Journal Article): Lentivirus-mediated Bcl-2 expression in betaTC-tet cells improves resistance to hypoxia and cytokine-induced apoptosis while preserving in vitro and in vivo control of insulin secretion.

Dupraz P, Rinsch C, Pralong WF, Rolland E, Zufferey R, Trono D, Thorens B
 
ABSTRACT: betaTC-tet cells are conditionally immortalized pancreatic beta cells which can confer long-term correction of hyperglycemia when transplanted in syngeneic streptozocin diabetic mi...

 

 

125. (Journal Article): Effects of C-peptide on expression of endothelial NOS (eNOS) and inducible NOS (iNOS) in human cavernosal smooth muscle cell.

Li H, Xu L, Dunbar JC, Dhabuwala CB, Sima AAF
 
ABSTRACT: OBJECTIVES: To investigate the role of C-peptide alone or in conjunction with insulin on the expression of nitric oxide synthase (NOS) in human corpus cavernosum smooth muscle cell...

 

 

126. (Journal Article): Proteomic analysis reveals alterations in the renal kallikrein pathway during hypoxia-induced hypertension.

Thongboonkerd V, Thongboonkerd V, Gozal E, Sachleben LR Jr, Arthur JM, Pierce WM, Cai J, Chao J, Bader M, Pesquero JB, Gozal D, Klein JB
 
ABSTRACT: Obstructive sleep apnea syndrome (OSAS), a disorder characterized by episodic hypoxia (EH) during sleep, is associated with systemic hypertension. We used proteomic analysis to exa...

 

 

127. (Journal Article): Renal calcium and magnesium handling in experimental diabetes mellitus in the rat.

Anwana AB, Garland HO
 
ABSTRACT: Metabolic and renal clearance techniques were used to examine kidney function in conscious and anesthetised streptozotocin diabetic rats. All diabetics showed an enhanced calcium a...

 

 

128. (Journal Article): Sodium loading changes urinary excretion: A proteomic analysis.

Thongboonkerd V, Klein JB, Pierce WM, Jevans AW, Arthur JM
 
ABSTRACT: Plasma sodium concentration is maintained even when sodium intake is altered. Sodium homeostasis may involve changes in renal tubular protein expression that are reflected in the u...

 

 

129. (Journal Article): Proteomic identification of a large complement of rat urinary proteins.

Thongboonkerd V, Klein JB, Arthur JM
 
ABSTRACT: The characterization of urinary proteins is an important tool to identify disease-related biomarkers and to better understand renal physiology. Expression of urinary proteins has b...

 

 

130. (Journal Article): Proteomic analysis of CA1 and CA3 regions of rat hippocampus and differential susceptibility to intermittent hypoxia.

Gozal E, Gozal D, Pierce WM, Thongboonkerd V, Scherzer JA, Sachleben LR Jr, Brittian KR, Guo SZ, Cai J, Klein JB.
 
ABSTRACT: The CA1 and CA3 regions of the hippocampus markedly differ in their susceptibility to hypoxia in general, and more particularly to the intermittent hypoxia that characterizes sleep...

 
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