Isolated Islet Cells

Sub-Areas to Isolated Islet Cells:

Functional Capability of Cells (0)
Stimulation of Division (1)
Endocrine Cells (3)
Ductal Cell Sources (4)
Cardiomyocytes (1)


(Journal Article): Large scale isolation, growth, and function of porcine neonatal islet cells.
 
Korbutt GS, Elliot JF, Ao Z, Smith DK, Warnock GL, Rajotte RV
 
IN: J Clin Invest 1996; 97(9):2119-2129
Impact Factor(s) of J Clin Invest: 14.204 (2004), 14.307 (2003), 14.118 (2001)

ABSTRACT: Based upon existing methods of isolating fetal porcine islet tissue, a simple, reliable procedure was developed for the preparation of porcine neonatal islet cell aggregates with a... Click HERE for details

 

(Journal Article): Cell loss in isolated human islets occurs by apoptosis.
 
Paraskevas S, Maysinger D, Wang R, Duguid TP, Rosenberg L
 
IN: Pancreas 2000; 20(3):270-276
Impact Factor(s) of Pancreas: 1.872 (2004), 1.855 (2003), 1.456 (2002), 1.567 (2001)

ABSTRACT: Purified islet allografts have largely failed to maintain long-term glucose homeostasis in human recipients, and the reasons for this are unclear. It is noteworthy, however, that i... Click HERE for details

 

(Journal Article): Pancreas preservation by the two layer cold storage method before islet isolation protects isolated islets against apoptosis through the mitochondrial pathway.
 
Matsuda T, Suzuki Y, Tanioka Y, Toyama H, Kakinoki K, Hiraoka K, Fujino Y, Kuroda Y
 
IN: Surgery 2003; 134(3):437-445
Impact Factor(s) of Surgery: 2.355 (2004), 2.611 (2003), 2.631 (2002), 2.615 (2001)

ABSTRACT: BACKGROUND: Apoptosis in isolated islets has been implicated in primary nonfunction or early graft failure after islet transplantation. Recently, pancreas preservation by the 2-lay... Click HERE for details

 

(Journal Article): Phosphatidylinositol 3-kinase signaling to Akt mediates survival in isolated canine islets of Langerhans.
 
Aikin R, Rosenberg L, Maysinger D
 
IN: Biochem Biophys Res Commun 2000; 277(2):455-461
Impact Factor(s) of Biochem Biophys Res Commun: 2.904 (2004), 2.836 (2003), 2.935 (2002), 2.946 (2001)

ABSTRACT: The isolation of islet cells from the pancreas by enzymatic digestion causes many of these cells to undergo apoptosis. The aim of this work was to investigate the role of phosphati... Click HERE for details

 

(Journal Article): Sustained proliferation of PDX-1 (+) cells derived from human islets.
 
Beattie GM, Itkin-Ansari P, Cirulli V, Leibowitz G, Lopez AD, Bossie S, Mally MI, Levine F, Hayek A
 
IN: Diabetes 1999; 48(5):1013-1019
Impact Factor(s) of Diabetes: 8.848 (2004), 8.298 (2003), 8.256 (2002), 7.7 (2001)

ABSTRACT: Ex vivo expansion of human beta-cells is an important step toward the development of cell-based insulin delivery systems in type 1 diabetes. Here, we report that human pancreatic e... Click HERE for details

 



 
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