Sub-Areas to NF-κB:
(Journal Article): A compre-hensive analysis of cytokine-induced and nuclear factor-kappa B-dependent genes in primary rat pancreatic beta-cells.
Cardozo AK, Heimberg H, Heremans Y, Leeman R, Kutlu B, Kruhoffer M, Orntoft T, Eizirik DL
IN:
J Biol Chem
2001; 276(52):48879-48886
Impact Factor(s) of J Biol Chem: 6.355 (2004), 6.482 (2003), 7.258 (2001)
ABSTRACT: Type 1 diabetes mellitus results from an autoimmune destruction of pancreatic beta-cells. Cytokines, such as interleukin-1 beta and interferon-gamma, are putative mediators of immu... Click HERE for details
(Journal Article): NOD mice are defective in proteasome production and activation of NF-kappaB.
Hayashi T, Faustman D
IN:
Mol Cell Biol
1999; 19(12):8646-8659
Impact Factor(s) of Mol Cell Biol: 7.822 (2004), 8.142 (2003), 8.84 (2002), 9.836 (2001)
ABSTRACT: The nonobese diabetic (NOD) mouse is an animal model of human type I diabetes with a strong genetic component that maps to the major histocompatibility complex (MHC) of the genome.... Click HERE for details
(Journal Article): Characterization of a nuclear-factor-kappa B (NFkappaB) genetic marker in type 1 diabetes (T1DM) families.
Gylvin T, Bergholdt R, Nerup J, Pociot F
IN:
Genes Immun
2002; 3(7):430-432
Impact Factor(s) of Genes Immun: 3.718 (2004), 3.637 (2003), 3.06 (2002), 3.787 (2001)
ABSTRACT: Cytokine-induced beta-cell death is an important factor in the pathogenesis of type 1 diabetes mellitus (T1DM). The transcription factor NFkappaB plays an important role in cytokin... Click HERE for details
(Journal Article): NFkappaB1 (p50)-deficient mice are not susceptible to multiple low-dose streptozotocin-induced diabetes.
Mabley JG, Hasko G, Liaudet L, Soriano F, Southan GJ, Salzman AL, Szabo C
IN:
J Endocrinol
2002; 173(3):457-464
Impact Factor(s) of J Endocrinol: 3.319 (2004), 3.023 (2003), 2.834 (2001)
ABSTRACT: Insulin-dependent diabetes mellitus (IDDM) is a disease characterized by the autoimmune destruction of the pancreatic beta-cells, which requires the expression of a number of immun... Click HERE for details
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