(Journal Article): Will C-Peptide Substitution Make a Difference in Combating Complications in Insulin-Deficient Diabetes?
 
Sima AAF (Departments of Pathology and Neurology, Wayne State University, 540 E. Canfield Avenue, Detroit, MI 48201, USA, asima(at)med.wayne.edu )
 
IN: Rev Diabetic Stud 2004; 1(2):55-57
Impact Factor(s) of Rev Diabetic Stud: 0.125 (2006)

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ABSTRACT: Not available.

TYPE OF PUBLICATION: Editorial

REFERENCES:

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  2. Sima AAF (ed). Physiological and pathophysiological significance of C-peptide actions. Exp Diab Res 2004. 5:1-96. [DOD]
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  12. Li Z-G, Zhang W, Sima AAF. C-peptide enhances insulin-mediated cell growth and protection against high glucose induced apoptosis in SH-SY5Y cells. Diab Metab Res Rev 2003. 19:375-385. [DOD]
  13. Pierson CR, Zhang W, Sima AAF. Proinsulin C-peptide replacement in type 1 diabetic BB/Wor-rats prevents deficits in nerve fiber regeneration. J Neuropath Exp Neurology 2003. 62:765-779. [DOD]
  14. Sima AAF, Zhang W, Li Z-G, Murakawa Y, Pierson CR. Molecular alterations underlie nodal and paranodal degenera-tion in type 1 diabetic neuropathy and are prevented by C-peptide. Diabetes 2004. 53:1556-1563. [DOD]
  15. Johansson B-L, Linde B, Wahren J. Effects of C-peptide on blood flow, capillary diffusion capacity and glucose utilization in the exercising forearm of type 1 (insulin-dependent) diabetic patients. Diabetologia 1992. 35:1151-1158. [DOD]
  16. Forst T, Kunt T, Pohlmann T, Goitom K, Engelbach M, Beyer J, Pfutzner A. Biological activity of C-peptide on the skin microcirculation in patients with insulin-dependent diabetes mellitus. J Clin Invest 1998. 101:2036-2041. [DOD]
  17. Johansson B-L, Borg K, Fernquist-Forbes E, Kernell A, Odergren T, Wahren J. Beneficial effects of C-peptide on incipient nephropathy and neuropathy in patients with type 1 diabetes mellitus. Diabetes Med 2000. 17:181-189. [DOD]
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  20. Zhang W, Yorek M, Pierson CR, Murakawa Y, Breidenbach A, Sima AAF. Human C-peptide dose dependently prevents early neuropathy in the BB/Wor-rat. Internatl J Exp Diab Res 2001. 2(3):187-194. [DOD]
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  22. Forst T, Kunt T. Effects of C-peptide on microvascular blood flow and blood hemorheology. Exp Diab Res 2004. 5:51-64. [DOD]
  23. Li Z-G, Zhang W, Sima AAF. C-peptide prevents hippocampal apoptosis in type 1 diabetes. Internatl J Exp Diab Res 2002. 3:241-246. [DOD]
  24. Sima AAF, Kamiya H. The changing view of diabetic neuropathy. Science Med (in press). [DOD]
  25. Li H, Xu L, Dunbar JC, Dhabuwala CB, Sima AAF. Effects of C-peptide on expression of endothelial NOS (eNOS) and inducible NOS (iNOS) in human cavernosal smooth muscle cell. J Urol (in press). [DOD]
  26. Stevens MJ, Zhang W, Li F, Sima AAF. C-peptide corrects endoneurial blood flow but not oxidative stress in type 1 BB/Wor-rats. Am J Physiol (in press). [DOD]


 
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